Evidence map›Paper›PMID 30263769›Full record

ArticleFood science and biotechnology2018

Application of stabilizer improves stability of nanosuspended branched-chain amino acids and anti-inflammatory effect in LPS-induced RAW 264.7 cells.

Hyun Suk Kim, Hyung-Seok Yu, Jae Hoon Lee, Gyu Whan Lee, Seung Jun Choi, Pahn-Shick Chang, Hyun-Dong Paik

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Food science and biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Nutrients · 2020
    Article
  4. Food science and biotechnology · 2020
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hyun Suk Kim1Department of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul, 05029 Korea.
Hyung-Seok Yu1Department of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul, 05029 Korea.
Jae Hoon Lee1Department of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul, 05029 Korea.
Gyu Whan LeeR&D Center, Daesang Corporation, Icheon, Gyoenggi-do 17384 Korea.
Seung Jun Choi3Department of Food Science and Technology, Seoul National University of Science and Technology, Seoul, 01811 Korea.
Pahn-Shick Chang4Department of Agricultural Biotechnology, Seoul National University, Seoul, 08826 Korea.
Hyun-Dong Paik1Department of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul, 05029 Korea.ORCID 0000-0001-9891-7703

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated the use of polyglyceryl esters (PGE) as stabilizer in improving stability and anti-inflammatory activity of nanosuspended branched-chain amino acids (BCAAs). BCAAs nanosuspended with stabilizer (BS) exhibited improved stability at concentration of 5% saturation level during storage as compared to BCAAs nanosuspended with aqueous solution (BA). Additionally, anti-inflammatory activity of BS was found to be greater than that of BA. Nitric oxide scavenging activity was found to be dose-dependent, with activity of BS in sodium nitroprusside system being significantly higher than that of BA (

Indexed as

Anti-inflammatoryBranched-chain amino acidsHigh pressure homogenizationRAW 264.7 macrophagesStabilizer

Identifiers

PMID30263769
PMCPMC6049625

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.