Evidence map›Paper›PMID 30263499›Full record

ArticleFood science and biotechnology2016

Data mining of micrornas in breast carcinogenesis which may be a potential target for cancer prevention.

Jin-Wook Kang, Min-Ji Kim, Hyun-Ah Baek, Jeong-Sang Lee

Abstract read
In one paragraph

Article in Food science and biotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jin-Wook Kang1Molecular Mechanisms of Functional Foods Laboratory, Jeonju University, Jeonju, Jeonbuk, 55069 Korea.
Min-Ji Kim1Molecular Mechanisms of Functional Foods Laboratory, Jeonju University, Jeonju, Jeonbuk, 55069 Korea.
Hyun-Ah Baek3Food Industry Research Institute, Jeonju University, Jeonju, Jeonbuk, 55069 Korea.
Jeong-Sang Lee1Molecular Mechanisms of Functional Foods Laboratory, Jeonju University, Jeonju, Jeonbuk, 55069 Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The microRNAs (miRNAs) negatively regulate the stability and translation of target messenger RNAs by selectively binding. It has been implicated in diverse processes such as cellular differentiation, cell-cycle control, apoptosis, and carcinogenesis. Examination of tumor-specific miRNA expression profiles has revealed wide spread dysregulation of these molecules in diverse cancers. The available genomic bulk evidences were extracted from The Cancer Genome Atlas by using IluminaGA_miRNASeq platform in human breast cancer samples. After mining collected data, group of each miRNA ID was analyzed through five D/Bs (mirWalk, miranda, mirDB, RNA22, and TargetScan) on predicted and validated miRNA targets. Oncogenes known to have a high correlation with breast cancer (

Indexed as

breast cancerchemopreventiondata miningmicroRNAtarget

Identifiers

PMID30263499
PMCPMC6049403

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.