Evidence map›Paper›PMID 30263494›Full record

ArticleFood science and biotechnology2016

Porcine hemoglobin promotes lipid excretion to feces more strongly than globin protein in rats.

Ryota Hosomi, Ren Otsuka, Hirofumi Arai, Seiji Kanda, Toshimasa Nishiyama, Munehiro Yoshida, Kenji Fukunaga

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Food science and biotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Cocoa (Foods (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ryota Hosomi1Laboratory of Food and Nutritional Sciences, Faculty of Chemistry, Materials, and Bioengineering, Kansai University, Osaka, 564-8680 Japan.
Ren Otsuka1Laboratory of Food and Nutritional Sciences, Faculty of Chemistry, Materials, and Bioengineering, Kansai University, Osaka, 564-8680 Japan.
Hirofumi Arai2Department of Biotechnology and Environmental Chemistry, Kitami Institute of Technology, Kitami, Hokkaido, 090-8507 Japan.
Seiji Kanda3Department of Public Health, Kansai Medical University, Osaka, 573-1010 Japan.
Toshimasa Nishiyama3Department of Public Health, Kansai Medical University, Osaka, 573-1010 Japan.
Munehiro Yoshida1Laboratory of Food and Nutritional Sciences, Faculty of Chemistry, Materials, and Bioengineering, Kansai University, Osaka, 564-8680 Japan.
Kenji Fukunaga1Laboratory of Food and Nutritional Sciences, Faculty of Chemistry, Materials, and Bioengineering, Kansai University, Osaka, 564-8680 Japan.
Kansai University · JPKansai Medical University · JPKitami Institute of Technology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In an effort to clarify whether the lipid-lowering effect of hemoglobin is due to globin protein or heme, this study investigated the effects of dietary porcine hemoglobin (PH) and porcine globin (PG) on lipids contents of serum, liver, and feces in rats. Five-week-old male Wistar rats were divided into 3 dietary groups of 7 rats each, with one group receiving a control diet and the other groups receiving diets containing 1.25% (w/w) PH or 1.18% (w/w) PG for 4 weeks. The PH diet decreased triacylglycerol content in serum and cholesterol in serum and liver, whereas the PG diet reduced triacylglycerol content in serum and cholesterol in liver. Fecal lipid excretion in the PH group was significantly higher than in the PG group. Therefore, PH affected lipid excretion to feces due to globin protein as well as heme.

Indexed as

cholesterolglobinhemelipid excretionporcine hemoglobin

Identifiers

PMID30263494
PMCPMC6049412
OpenAlexW2343848757

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.