Evidence map›Paper›PMID 30263134›Full record

ArticleGlobal health, epidemiology and genomics2018

Association between multimorbidity and undiagnosed obstructive sleep apnea severity and their impact on quality of life in men over 40 years old.

G Ruel, S A Martin, J-F Lévesque, G A Wittert, R J Adams, S L Appleton, Z Shi, A W Taylor

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Global health, epidemiology and genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
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  17. Prevalence and Sources of Errors in Positive Airway Pressure Therapy Provisioning.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2019
    Article
  18. Obstructive sleep apnea and comorbidities: a dangerous liaison.Multidisciplinary respiratory medicine · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

G RuelDirection québécoise du cancer, Ministère de la Santé et des Services sociaux, Québec, Canada.
S A MartinDiscipline of Medicine, University of Adelaide, South Australia, Australia.
J-F LévesqueCentre de recherche du CHUM, Université de Montréal, Montréal, Canada.
G A WittertDiscipline of Medicine, University of Adelaide, South Australia, Australia.
R J AdamsDiscipline of Medicine, University of Adelaide, South Australia, Australia.
S L AppletonDiscipline of Medicine, University of Adelaide, South Australia, Australia.
Z ShiDiscipline of Medicine, University of Adelaide, South Australia, Australia.
A W TaylorDiscipline of Medicine, University of Adelaide, South Australia, Australia.
University of Adelaide · AUCentre Hospitalier de l’Université de Montréal · CAMinistry of Health and Social Services · CAQueen Elizabeth Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMultimorbidity is common but little is known about its relationship with obstructive sleep apnea (OSA).

methodsMen Androgen Inflammation Lifestyle Environment and Stress Study participants underwent polysomnography. Chronic diseases (CDs) were determined by biomedical measurement (diabetes, dyslipidaemia, hypertension, obesity), or self-report (depression, asthma, cardiovascular disease, arthritis). Associations between CD count, multimorbidity, apnea-hyponea index (AHI) and OSA severity and quality-of-life (QoL; mental & physical component scores), were determined using multinomial regression analyses, after adjustment for age.

resultsOf the 743 men participating in the study, overall 58% had multimorbidity (2+ CDs), and 52% had OSA (11% severe). About 70% of those with multimorbidity had undiagnosed OSA. Multimorbidity was associated with AHI and undiagnosed OSA. Elevated CD count was associated with higher AHI value and increased OSA severity.

conclusionWe demonstrate an independent association between the presence of OSA and multimorbidity in this representative sample of community-based men. This effect was strongest in men with moderate to severe OSA and three or more CDs, and appeared to produce a greater reduction in QoL when both conditions were present together.

Indexed as

Apnea-hypopnea indexchronic diseasecomorbidityobstructive sleep apneaquality of life

Identifiers

PMID30263134
PMCPMC6152492
OpenAlexW2806482127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.