Evidence map›Paper›PMID 30263133›Full record

ReviewGlobal health, epidemiology and genomics2018

Strategies for screening cord blood for a public cord blood bank in high HIV prevalence regions.

M Meissner-Roloff, L Gaggia, M Vermeulen, A F H Mazanderani, N M du Plessis, H C Steel, M S Pepper

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Global health, epidemiology and genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

M Meissner-RoloffDepartment of Immunology, Institute for Cellular and Molecular Medicine, Faculty of Health Sciences, and SAMRC Extramural Unit for Stem Cell Research and Therapy, University of Pretoria, Pretoria, South Africa.
L GaggiaSouth African National Blood Service, 1 Constantia Boulevard, Constantia Kloof Ext. 22, Weltevreden Park, South Africa.
M VermeulenSouth African National Blood Service, 1 Constantia Boulevard, Constantia Kloof Ext. 22, Weltevreden Park, South Africa.
A F H MazanderaniNational Institute for Communicable Diseases, National Health Laboratory Services, 1 Modderfontein Road, Sandringham, South Africa.
N M du PlessisDepartment of Paediatrics, Kalafong Provincial Tertiary Hospital and Faculty of Health Sciences, University of Pretoria, Private Bag X396, Pretoria, South Africa.
H C SteelDepartment of Immunology, Institute for Cellular and Molecular Medicine, Faculty of Health Sciences, and SAMRC Extramural Unit for Stem Cell Research and Therapy, University of Pretoria, Pretoria, South Africa.
M S PepperDepartment of Immunology, Institute for Cellular and Molecular Medicine, Faculty of Health Sciences, and SAMRC Extramural Unit for Stem Cell Research and Therapy, University of Pretoria, Pretoria, South Africa.
South African National Blood Service · ZAUniversity of Pretoria · ZAKalafong Hospital · ZANational Health Laboratory Service · ZASouth African Medical Research Council · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The probability of a Black African finding a matched unrelated donor for a hematopoietic stem cell transplant is minimal due to the high degree of genetic diversity amongst individuals of African origin. This problem could be resolved in part by the establishment of a public cord blood (CB) stem cell bank. The high prevalence of human immunodeficiency virus (HIV) amongst women attending antenatal clinics in sub-Saharan Africa together with the risk of mother-to-child transmission increases the risk of transplant transmissible infection. In addition to screening the mother in a period inclusive of 7 days prior to the following delivery, we propose that all CB units considered for storage undergo rigorous and reliable screening for HIV. The Ultrio-plus

Indexed as

AfricaART, anti-retroviral therapyCMV, cytomegaloviruscord bloodDNA, deoxyribonucleic acidELISA, enzyme-linked immunosorbent assayEPI, Expanded Programme of ImmunisationFDA, Food and Drug AdministrationHBV, hepatitis B virusHCV, hepatitis C virusHIVHIV, human immunodeficiency virusHLA, human leukocyte antigenHSCT, haematopoietic stem cell transplantationMTCT, mother-to-child transmissionNAT, nucleic acid testPCR, polymerase chain reactionPMTCT, prevention of mother-to-child transmissionRNA, ribonucleic acidSABMR, South African Bone Marrow RegistrySANBS, South African National Blood Servicestem cellTNC, total nucleated celltransplantationUCB, umbilical cord bloodWMDA, World Marrow Donor Association

Identifiers

PMID30263133
PMCPMC6152491
OpenAlexW2803562207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.