Evidence map›Paper›PMID 30263132›Full record

ReviewGlobal health, epidemiology and genomics2018

Genetics of breast cancer in African populations: a literature review.

A Abbad, H Baba, H Dehbi, M Elmessaoudi-Idrissi, Z Elyazghi, O Abidi, F Radouani

Open access · goldAbstract readReview
In one paragraph

Review in Global health, epidemiology and genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Review
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  10. PioneeringFrontiers in oncology · 2021
    Article
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  13. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

A AbbadLaboratoire d'écologie et d'environnement- Faculté des Sciences Ben M'sik, Université Hassan II de Casablanca, Casablanca, Morocco.
H BabaLaboratoire de Biologie et santé - URAC34, Modélisation Moléculaire et Contrôle Qualité, Faculté des Sciences Ben M'sik, Université Hassan II de Casablanca, Morocco.
H DehbiLaboratoire de Pathologies Cellulaires et Moléculaires- Faculté de Médecine et de Pharmacie de Casablanca, Université Hassan II de Casablanca, Morocco.
M Elmessaoudi-IdrissiLaboratoire de Biologie et santé - URAC34, Modélisation Moléculaire et Contrôle Qualité, Faculté des Sciences Ben M'sik, Université Hassan II de Casablanca, Morocco.
Z ElyazghiPhysiology and Physiopathology Team, Immunogenomic and Bioinformatic Unit, Faculty of Sciences, Genomic Center of Human Pathologies, Mohammed V University of Rabat, Morocco.
O AbidiHuman Molecular Genetics and Medical Genomics Laboratory, Institut Supérieur des Professions Infirmières et Techniques de Santé (ISPITS) de Casablanca, Ministère de la Santé, Morocco.
F RadouaniChlamydiae and Mycoplasma Laboratory, Institut Pasteur du Maroc, Casablanca, Morocco.ORCID 0000-0002-6221-2661
Institut Pasteur du Maroc · MACentre Hospitalier Universitaire Ibn Rochd · MAInstituts Supérieurs des Professions Infirmières et Techniques de Santé · MAMohammed V University · MA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer (BC) is one of the most complex, diverse and leading cause of death in women worldwide. The present investigation aims to explore genes panel associated with BC in different African regions, and compare them to those studied worldwide. We extracted relevant information from 43 studies performed in Africa using the following criteria: case-control study, association between genetic variations and BC risk. Data were provided on mutations and polymorphisms associated with BC without fixing a specific date. Case-only studies and clinical trials were excluded. Our study revealed that the majority of African BC genetic studies remain restricted to the investigation of BRCA1 and BRCA2 genes and differences in their mutations spectrum. Therefore, it is necessary to encourage African researchers to characterize more genes involved in BC using methods generating global information such as next-generation sequencing in order to guide specific and more effective therapeutic strategies for the African community.

Indexed as

Africabreast cancergeneticsgenetic variability

Identifiers

PMID30263132
PMCPMC6152487
OpenAlexW2803671180

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.