Evidence map›Paper›PMID 30262856›Full record

ArticleScientific reports2018

Identification of Peptide Mimotope Ligands for Natalizumab.

Laura E Ruff, Jessica A Pfeilsticker, Nicholas E Johnsen, Sarah Nocchi, Bradley T Messmer

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. DPL: a comprehensive database on sequences, structures, sources and functions of peptide ligands.Database : the journal of biological databases and curation · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Laura E RuffAbreos Biosciences, 3550 General Atomics Ct, Bldg G02, Rm 137, San Diego, CA, 92121, USA.
Jessica A PfeilstickerAbreos Biosciences, 3550 General Atomics Ct, Bldg G02, Rm 137, San Diego, CA, 92121, USA.
Nicholas E JohnsenAbreos Biosciences, 3550 General Atomics Ct, Bldg G02, Rm 137, San Diego, CA, 92121, USA.
Sarah NocchiAbreos Biosciences, 3550 General Atomics Ct, Bldg G02, Rm 137, San Diego, CA, 92121, USA.
Bradley T MessmerAbreos Biosciences, 3550 General Atomics Ct, Bldg G02, Rm 137, San Diego, CA, 92121, USA. bmessmer@abreosbio.com.
Abreos Biosciences (United States) · USGeneral Atomics (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mimotope peptides selected from combinatorial peptide libraries can be used as capture reagents for immunoassay detection of therapeutic monoclonal antibodies (mAbs). We report the use of phage display libraries to identify peptide ligands (Veritopes

Indexed as

Peptide LibraryAmino Acid MotifsEpitopesHumansIntegrin alpha4NatalizumabEpitopesIntegrin alpha4NatalizumabPeptide Library

Identifiers

PMID30262856
PMCPMC6160459
OpenAlexW2890229042

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.