ArticleScience (New York, N.Y.)2018
Biosynthesis of the neurotoxin domoic acid in a bloom-forming diatom.
Open access · greenAbstract read
In one paragraph
Article in Science (New York, N.Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.
0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed
10.5field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
78 citing papers in PubMed, 210 citations in OpenAlex.
- Divergent Lineage of Terpene Synthases Establishes Terpenoid Biosynthesis in Brown Macroalgae.Journal of the American Chemical Society · 2026Article
- Algal bioactive compounds for next-generation biopesticides: a multi-target resource for sustainable pest management.Environmental science and pollution research international · 2026Review
- Biosynthesis of Kaitocephalin: A Neuroprotective Natural Product Featuring a Peptide-Like yet Nonpeptidic Scaffold.Angewandte Chemie (International ed. in English) · 2026Article
- Tracing the origin and evolution of specialized biosynthetic pathways in marine organisms.mBio · 2026Article
- Real-Time Tracking of Intracellular Prenyl Phosphate Pools in the Marine DiatomACS synthetic biology · 2026Article
- A high-throughput biocatalytic platform for screening isomeric kainoid natural products.Cell reports. Physical science · 2026Article
- CURE-ating the Substrate Scope and Functional Residues of Nonheme Iron(II) α-Ketoglutarate-Dependent Hydroxylase BesE.Journal of natural products · 2026Article
- Molecular and Cellular Mechanisms Underlying Domoic Acid-Induced Neurotoxicity and Therapeutic Drugs: A Comprehensive Review.International journal of molecular sciences · 2026Review
- Some Bioactive Natural Products from Diatoms: Structures, Biosyntheses, Biological Roles, and Properties: 2015-2025.Marine drugs · 2026Review
- Biologically Active Molecules from Marine Brown Algae: A Review of Their Potential and Applications.Chemistry & biodiversity · 2026Review
- Article
- Domoic Acid Risk and the Potential of Meta-Omics for Environmental Surveillance.Global change biology · 2025Article
- Article
- A High-Throughput Biocatalytic Platform for Screening Isomeric Kainoid Natural Products.bioRxiv : the preprint server for biology · 2025Article
- Multiple Catalytic Branch Points in the Mechanism of Pyrrolidine Formation During Kainoid Biosynthesis Leads to Diverse Reaction Outcomes.Journal of the American Chemical Society · 2025Article
- Progress and prospects in metabolic engineering approaches for isoprenoid biosynthesis in microalgae.Biotechnology for biofuels and bioproducts · 2025Review
- Phylogenomics reveals the slow-burning fuse of diatom evolution.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Remodeling of the terpenoid metabolism during prolonged phosphate depletion in the marine diatom Phaeodactylum tricornutum.Journal of phycology · 2025Article
- Discovery of Noncanonical Iron and 2-Oxoglutarate Dependent Enzymes Involved in C-C and C-N Bond Formation in Biosynthetic Pathways.ACS bio & med chem Au · 2025Review
- Sexual reproduction during diatom bloom.ISME communications · 2025Article
18 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
13 authors at 6 institutions in 2 countries.
John K BrunsonCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA 92093, USA.ORCID 0000-0002-6288-5110
Shaun M K McKinnieCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA 92093, USA.ORCID 0000-0001-6776-6455
Jonathan R ChekanCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA 92093, USA.ORCID 0000-0003-4651-0594
John P McCrowMicrobial and Environmental Genomics Group, J. Craig Venter Institute, La Jolla, CA 92037, USA.
Zachary D MilesCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA 92093, USA.
Erin M BertrandMicrobial and Environmental Genomics Group, J. Craig Venter Institute, La Jolla, CA 92037, USA.ORCID 0000-0002-5950-6810
Vincent A BielinskiSynthetic Biology and Bioenergy Group, J. Craig Venter Institute, La Jolla, CA 92037, USA.ORCID 0000-0002-8107-8752
Hanna LuhavayaCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA 92093, USA.
Miroslav OborníkInstitute of Parasitology, University of South Bohemia and Biology Center CAS, Branišovská 31, 370 05 České Budějovice, Czech Republic.
G Jason SmithMoss Landing Marine Laboratories, 8272 Moss Landing Road, Moss Landing, CA 95039, USA.ORCID 0000-0003-1258-4800
David A HutchinsMarine and Environmental Biology, Department of Biological Sciences, University of Southern California, Los Angeles, CA 90089, USA.ORCID 0000-0002-6637-756X
Andrew E AllenMicrobial and Environmental Genomics Group, J. Craig Venter Institute, La Jolla, CA 92037, USA. bsmoore@ucsd.edu aallen@jcvi.org.ORCID 0000-0001-5911-6081
Bradley S MooreCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA 92093, USA. bsmoore@ucsd.edu aallen@jcvi.org.ORCID 0000-0002-4652-1253
Scripps Institution of Oceanography · USJ. Craig Venter Institute · USDalhousie University · CAMoss Landing Marine Laboratories · USSewanee: The University of the South · USUniversity of Southern California · US
Funding
Sources and Sins of Halogenated Organic Compounds in the Marine EnvironmentP01ES021921 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MOORE, BRADLEY S · 2012 to 2016
$1.9MChemical Biology Interfaces at UC San DiegoT32GM112584 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BURKART, MICHAEL D. · 2015 to 2019
$729kNIEHS NIH HHS P01 ES021921NIGMS NIH HHS T32 GM112584
Abstract
Oceanic harmful algal blooms of
Indexed as
EutrophicationDiatomsKainic AcidMultigene FamilyNeurotoxinsRecombinant Proteinsdomoic acidKainic AcidNeurotoxinsRecombinant Proteins
Identifiers
What OpenQuestion holds
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.