Evidence map›Paper›PMID 30262458›Full record

ArticleRNA (New York, N.Y.)2018

The DEAD-box protein Dbp2p is linked to noncoding RNAs, the helicase Sen1p, and R-loops.

Frank A Tedeschi, Sara C Cloutier, Elizabeth J Tran, Eckhard Jankowsky

Abstract read
In one paragraph

Article in RNA (New York, N.Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Gle1 is required for tRNA to stimulate Dbp5 ATPase activitybioRxiv : the preprint server for biology · 2023
    Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. R-Loop-Associated Genomic Instability and Implication of WRN and WRNIP1.International journal of molecular sciences · 2022
    Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. TheRNA (New York, N.Y.) · 2020
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Frank A TedeschiCenter for RNA Science and Therapeutics, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106, USA.
Sara C CloutierDepartment of Biochemistry, Purdue University, West Lafayette, Indiana 47907, USA.
Elizabeth J TranDepartment of Biochemistry, Purdue University, West Lafayette, Indiana 47907, USA.
Eckhard JankowskyCenter for RNA Science and Therapeutics, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106, USA.

Funding

Enzymes and enzyme complexes in RNA metabolismR35GM118088 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI JANKOWSKY, ECKHARD · 2016 to 2022
$4.3M
The Role of DEAD-box Proteins in Gene ExpressionR01GM097332 · NIGMS · PURDUE UNIVERSITY · PI TRAN, ELIZABETH J · 2011 to 2025
$4.1M
NIGMS NIH HHS R01 GM097332NIGMS NIH HHS R35 GM118088NIH HHS GM097332NIH HHS GM118088
6 · The paper itself

Abstract

The DEAD-box RNA helicase Dbp2p is highly conserved in eukaryotes and has been implicated in transcription, ribosome biogenesis, mRNP assembly, nuclear export, and long noncoding RNA (lncRNA) function. It is not understood how Dbp2p performs these seemingly unrelated biological roles. An important step toward addressing this question is the determination of cellular RNA binding sites of Dbp2p. Here, we identify transcriptome-wide RNA binding sites of Dbp2p from

Indexed as

Binding SitesDEAD-box RNA HelicasesGene Expression Regulation, FungalProteasome Endopeptidase ComplexRNA-Binding ProteinsRNA, Small NuclearRNA, Small NucleolarRNA, TransferRNA, UntranslatedSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsDbp2 protein, S cerevisiaeDEAD-box RNA HelicasesProteasome Endopeptidase ComplexRNA-Binding ProteinsRNA, Small NuclearRNA, Small NucleolarRNA, TransferRNA, UntranslatedRPN2 protein, S cerevisiaeSaccharomyces cerevisiae ProteinshelicaseNNS complexnoncoding RNAnucleusR-loopssnoRNA

Identifiers

PMID30262458
PMCPMC6239179

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.