Evidence map›Paper›PMID 30262450›Full record

ArticleJMIR medical informatics2018

Extraction and Standardization of Patient Complaints from Electronic Medication Histories for Pharmacovigilance: Natural Language Processing Analysis in Japanese.

Misa Usui, Eiji Aramaki, Tomohide Iwao, Shoko Wakamiya, Tohru Sakamoto, Mayumi Mochizuki

Open access · goldAbstract read
In one paragraph

Article in JMIR medical informatics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Misa UsuiDivision of Hospital Pharmacy Science, Graduate School of Pharmaceutical Sciences, Keio University, Tokyo, Japan.ORCID http://orcid.org/0000-0002-4488-1079
Eiji AramakiSocial Computing Lab, Graduate School of Information Science, Nara Institute of Science and Technology, Nara, Japan.ORCID http://orcid.org/0000-0003-0201-3609
Tomohide IwaoSocial Computing Lab, Graduate School of Information Science, Nara Institute of Science and Technology, Nara, Japan.ORCID http://orcid.org/0000-0002-7400-8430
Shoko WakamiyaSocial Computing Lab, Graduate School of Information Science, Nara Institute of Science and Technology, Nara, Japan.ORCID http://orcid.org/0000-0002-9371-1340
Tohru SakamotoHolon Co, Ltd., Hiroshima, Japan.ORCID http://orcid.org/0000-0002-6444-6306
Mayumi MochizukiDivision of Hospital Pharmacy Science, Faculty of Pharmacy, Keio University, Tokyo, Japan.ORCID http://orcid.org/0000-0001-6772-4327
Nara Institute of Science and Technology · JPHolon Institute of Technology · ILKeio University · JPKeio University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite the growing number of studies using natural language processing for pharmacovigilance, there are few reports on manipulating free text patient information in Japanese.

objectiveThis study aimed to establish a method of extracting and standardizing patient complaints from electronic medication histories accumulated in a Japanese community pharmacy for the detection of possible adverse drug event (ADE) signals.

methodsSubjective information included in electronic medication history data provided by a Japanese pharmacy operating in Hiroshima, Japan from September 1, 2015 to August 31, 2016, was used as patients' complaints. We formulated search rules based on morphological analysis and daily (nonmedical) speech and developed a system that automatically executes the search rules and annotates free text data with International Classification of Diseases, Tenth Revision (ICD-10) codes. The performance of the system was evaluated through comparisons with data manually annotated by health care workers for a data set of 5000 complaints.

resultsOf 5000 complaints, the system annotated 2236 complaints with ICD-10 codes, whereas health care workers annotated 2348 statements. There was a match in the annotation of 1480 complaints between the system and manual work. System performance was .66 regarding precision, .63 in recall, and .65 for the F-measure.

conclusionsOur results suggest that the system may be helpful in extracting and standardizing patients' speech related to symptoms from massive amounts of free text data, replacing manual work. After improving the extraction accuracy, we expect to utilize this system to detect signals of possible ADEs from patients' complaints in the future.

Indexed as

adverse drug eventsmedical informaticsmedication historynatural language processingpharmacovigilance

Identifiers

PMID30262450
PMCPMC6231790
OpenAlexW2888190576

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.