ArticleAmerican journal of respiratory and critical care medicine2019
Albuminuria, Lung Function Decline, and Risk of Incident Chronic Obstructive Pulmonary Disease. The NHLBI Pooled Cohorts Study.
Article in American journal of respiratory and critical care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Microalbuminuria in patients with chronic obstructive pulmonary disease: A systematic review and meta-analysis.The Indian journal of medical research · 2026Pooled it
- Association of urinary albumin-to-creatinine ratio with all-cause and cardiovascular disease mortality risk in patients with osteoarthritis: a prospective cohort study.Clinical rheumatology · 2026Article
- Associations of albuminuria with interstitial lung abnormalities in older community-dwelling adults confounded by age.ERJ open research · 2025Article
- Article
- Association between measures of kidney function and preserved ratio impaired spirometry in diabetes: NHANES 2007-2012.BMJ open · 2024Article
- Association between pulmonary function and rapid kidney function decline: a longitudinal cohort study from CHARLS.BMJ open respiratory research · 2024Article
- Study on the relationship between body mass index and blood pressure indices in children aged 7-17 during COVID-19.Frontiers in public health · 2024Article
- Investigating Associations of Omega-3 Fatty Acids, Lung Function Decline, and Airway Obstruction.American journal of respiratory and critical care medicine · 2023Article
- Genomics of Treatable Traits in Asthma.Genes · 2023Review
- Mutual Effects of Coincident Chronic Renal Failure and Chronic Obstructive Pulmonary Disease.Tanaffos · 2023Article
- Association between serum creatinine levels and pulmonary function of Korean adults: the 2016-2019 Korea National Health and Nutrition Examination Survey.Physical activity and nutrition · 2023Article
- The Pleiotropic Role of Vitamin K in Multimorbidity of Chronic Obstructive Pulmonary Disease.Journal of clinical medicine · 2023Review
- Lung Dysfunction and Chronic Kidney Disease: A Complex Network of Multiple Interactions.Journal of personalized medicine · 2023Review
- Impact of albuminuria on the various causes of death in diabetic patients: a nationwide population-based study.Scientific reports · 2023Article
- Article
- Albuminuria as a Predictor of Mortality from Chronic Lower Respiratory Disease and from Influenza and Pneumonia.Annals of the American Thoracic Society · 2021Article
- Regional Gas Exchange Measured byJournal of magnetic resonance imaging : JMRI · 2021Article
- Protein Biomarkers for COPD Outcomes.Chest · 2021Review
- COPD significantly increases cerebral and cardiovascular events in hypertensives.Scientific reports · 2021Article
- Hospitalization Rates in Older Adults With Albuminuria: The Cardiovascular Health Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Article
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Authors and funding
17 authors at 13 institutions in 2 countries.
Funding
Abstract
rationaleChronic lower respiratory diseases (CLRDs), including chronic obstructive pulmonary disease (COPD) and asthma, are the fourth leading cause of death. Prior studies suggest that albuminuria, a biomarker of endothelial injury, is increased in patients with COPD.
objectivesTo test whether albuminuria was associated with lung function decline and incident CLRDs.
methodsSix U.S. population-based cohorts were harmonized and pooled. Participants with prevalent clinical lung disease were excluded. Albuminuria (urine albumin-to-creatinine ratio) was measured in spot samples. Lung function was assessed by spirometry. Incident CLRD-related hospitalizations and deaths were classified via adjudication and/or administrative criteria. Mixed and proportional hazards models were used to test individual-level associations adjusted for age, height, weight, sex, race/ethnicity, education, birth year, cohort, smoking status, pack-years of smoking, renal function, hypertension, diabetes, and medications. MEASUREMENTS AND MAIN
resultsAmong 10,961 participants with preserved lung function, mean age at albuminuria measurement was 60 years, 51% were never-smokers, median albuminuria was 5.6 mg/g, and mean FEV
conclusionsAlbuminuria was associated with greater lung function decline, incident spirometry-defined COPD, and incident COPD-related events in a U.S. population-based sample.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.