Evidence map›Paper›PMID 30261693›Full record

ArticleInternational journal of molecular sciences2018

Chemical Exposure-Induced Changes in the Expression of Neurotrophins and Their Receptors in the Main Olfactory System of Mice Lacking TRPM5-Expressing Microvillous Cells.

Abdullah AlMatrouk, Kayla Lemons, Tatsuya Ogura, Wangmei Luo, Chantel Wilson, Weihong Lin

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Chemosensory tobacco product toxicology part 1: sensory mechanisms.Toxicological sciences : an official journal of the Society of Toxicology · 2025
    Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Abdullah AlMatroukDepartment of Biological Sciences, University of Maryland, Baltimore County, Baltimore, MD 21250, USA. ow06215@umbc.edu.
Kayla LemonsDepartment of Biological Sciences, University of Maryland, Baltimore County, Baltimore, MD 21250, USA. kalem1@umbc.edu.
Tatsuya OguraDepartment of Biological Sciences, University of Maryland, Baltimore County, Baltimore, MD 21250, USA. tatsuya@umbc.edu.
Wangmei LuoDepartment of Biological Sciences, University of Maryland, Baltimore County, Baltimore, MD 21250, USA. wangmei.luo@yahoo.com.
Chantel WilsonDepartment of Biological Sciences, University of Maryland, Baltimore County, Baltimore, MD 21250, USA. wilson14@umbc.edu.
Weihong LinDepartment of Biological Sciences, University of Maryland, Baltimore County, Baltimore, MD 21250, USA. weihong@umbc.edu.
University of Maryland, Baltimore County · US

Funding

EXPAND PARTICIPATION BY MINORITIES IN BIOMEDICAL SCIENCER25GM055036 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI SUMMERS, MICHAEL FINLEY · 1996 to 2021
$16.9M
Xenobiotics detection in olfactory epitheliumR01DC012831 · NIDCD · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI LIN, WEIHONG · 2012 to 2016
$1.6M
National Institute on Deafness and Other Communication Disorders R01DC012831NIDCD NIH HHS R01 DC012831NIGMS NIH HHS R25 GM055036
6 · The paper itself

Abstract

Functional maintenance of the mammalian main olfactory epithelium (MOE) is challenging because of its direct exposure to a wide spectrum of environmental chemicals. We previously reported that transient receptor potential channel M5-expressing microvillous cells (TRPM5-MCs) in the MOE play an important role in olfactory maintenance. To investigate the underpinning mechanisms, we exposed transcription factor

Indexed as

AnimalsChitinEthylaminesFemaleMaleMiceMice, Inbred C57BLNerve Growth FactorsOctamer Transcription FactorsOlfactory Receptor NeuronsReceptors, Nerve Growth FactorTRPM Cation ChannelsChitinEthylaminesNerve Growth FactorsNgfr protein, mouseOctamer Transcription FactorsPou2f3 protein, mouseReceptors, Nerve Growth FactortriethylamineTrpm5 protein, mouseTRPM Cation Channelsmicrovillous cellsolfactory epithelial maintenanceolfactory sensory neuronsreal-time qPCRSkn-1a/Pou2f3

Identifiers

PMID30261693
PMCPMC6213160
OpenAlexW2892871007

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.