ArticleEndoscopy2019
Assessment of Barrett's esophagus and dysplasia with ultrahigh-speed volumetric en face and cross-sectional optical coherence tomography.
Article in Endoscopy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 14 citations in OpenAlex.
- Tethered optoacoustic and optical coherence tomography capsule endoscopy for label-free assessment of Barrett's oesophageal neoplasia.Nature biomedical engineering · 2026Article
- Ex vivo optical coherence tomography combined with near infrared targeted fluorescence: towardsBiomedical optics express · 2024Article
- Differential diagnosis of acute and chronic colitis in mice by optical coherence tomography.Quantitative imaging in medicine and surgery · 2022Article
- Dual-modality optical coherence tomography and fluorescence tethered capsule endomicroscopy.Biomedical optics express · 2021Article
- Shot-noise limited, supercontinuum-based optical coherence tomography.Light, science & applications · 2021Article
- Multi-MHz MEMS-VCSEL swept-source optical coherence tomography for endoscopic structural and angiographic imaging with miniaturized brushless motor probes.Biomedical optics express · 2021Article
- Correction of circumferential and longitudinal motion distortion in high-speed catheter/endoscope-based optical coherence tomography.Biomedical optics express · 2021Article
- Diagnosing colorectal abnormalities using scattering coefficient maps acquired from optical coherence tomography.Journal of biophotonics · 2021Article
- Advanced endoscopic imaging for detecting and guiding therapy of early neoplasias of the esophagus.Annals of the New York Academy of Sciences · 2020Review
- Tethered capsule en face optical coherence tomography for imaging Barrett's oesophagus in unsedated patients.BMJ open gastroenterology · 2020Article
- Optical coherence tomography-guided laser marking with tethered capsule endomicroscopy in unsedated patients.Biomedical optics express · 2019Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundThis study aimed to evaluate the use of ultrahigh-speed volumetric en face and cross-sectional optical coherence tomography (OCT) with micromotor catheters for the in vivo assessment of Barrett's esophagus and dysplasia.
methods74 OCT datasets with correlated biopsy/endoscopic mucosal resection histology (49 nondysplastic Barrett's esophagus [NDBE], 25 neoplasia) were obtained from 14 patients with Barrett's esophagus and a history of dysplasia and 30 with NDBE. The associations between irregular mucosal patterns on en face OCT, absence of mucosal layering, surface signal > subsurface, and > 5 atypical glands on cross-sectional OCT vs. histology and treatment history were assessed by three blinded readers.
resultsAtypical glands under irregular mucosal patterns occurred in 75 % of neoplasia (96 % of treatment-naïve neoplasia) vs. 30 % of NDBE datasets (43 % of short- and 18 % of long-segment NDBE). Mucosal layering was absent in 35 % of neoplasia and 50 % of NDBE datasets, and surface signal > subsurface occurred in 29 % of neoplasia and 30 % of NDBE datasets.
conclusionsAtypical glands under irregular mucosal patterns are strongly associated with neoplasia, suggesting potential markers for dysplasia and a role in pathogenesis.
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