ArticleAnnual review of psychology2019
An Integrated Model of Action Selection: Distinct Modes of Cortical Control of Striatal Decision Making.
Article in Annual review of psychology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.
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Who cites it
53 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Meta-analysis of reward processing in major depressive disorder reveals distinct abnormalities within the reward circuit.Translational psychiatry · 2019Pooled it
- Automatic value learning results in counterproductive human behavior.Nature communications · 2026Article
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- Prefrontal modulation of striatal engagement: a hierarchical framework for goal-directed behavior.Communications biology · 2026Review
- Medial prefrontal cortex activity precedes dorsomedial striatum in need for change during history-based flexible behavior.iScience · 2025Article
- Prefrontal Network Mechanisms of Psychiatric Deep Brain Stimulation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Review
- Absence of sex differences in serotonergic control of orbitofrontal cortex neuronal activity.Scientific reports · 2025Article
- Hippocampal output suppresses orbitofrontal cortex schema cell formation.Nature neuroscience · 2025Article
- Neurostimulation to Improve Cognitive Flexibility.Current opinion in behavioral sciences · 2025Article
- Article
- Dynamic responses of striatal cholinergic interneurons control behavioral flexibility.Science advances · 2024Article
- Cortico-striatal action control inherent of opponent cognitive-motivational styles.bioRxiv : the preprint server for biology · 2024Article
- Impaired striatal glutamate/GABA regulation in violent offenders with antisocial personality disorder and psychopathy.Molecular psychiatry · 2024Article
- Functional diversity of dopamine axons in prefrontal cortex during classical conditioning.eLife · 2024Article
- Adolescents rats engage the orbitofrontal-striatal pathway differently than adults during impulsive actions.Scientific reports · 2024Article
- Paternal cocaine-seeking motivation defines offspring's vulnerability to addiction by down-regulating GABAergic GABRG3 in the ventral tegmental area.Translational psychiatry · 2024Article
- Cholinergic Activation of Corticofugal Circuits in the Adult Mouse Prefrontal Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Prefrontal signals precede striatal signals for biased credit assignment in motivational learning biases.Nature communications · 2024Article
- The cognitive (lateral) hypothalamus.Trends in cognitive sciences · 2024Review
- Neural substrates of parallel devaluation-sensitive and devaluation-insensitive Pavlovian learning in humans.Nature communications · 2023Article
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Authors and funding
6 authors.
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Abstract
Making decisions in environments with few choice options is easy. We select the action that results in the most valued outcome. Making decisions in more complex environments, where the same action can produce different outcomes in different conditions, is much harder. In such circumstances, we propose that accurate action selection relies on top-down control from the prelimbic and orbitofrontal cortices over striatal activity through distinct thalamostriatal circuits. We suggest that the prelimbic cortex exerts direct influence over medium spiny neurons in the dorsomedial striatum to represent the state space relevant to the current environment. Conversely, the orbitofrontal cortex is argued to track a subject's position within that state space, likely through modulation of cholinergic interneurons.
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