Evidence map›Paper›PMID 30260731›Full record

ArticleJournal of palliative medicine2018

Frequency, Outcomes, and Associated Factors for Opioid-Induced Neurotoxicity in Patients with Advanced Cancer Receiving Opioids in Inpatient Palliative Care.

Kyu-Hyoung Lim, Nhu-Nhu Nguyen, Yu Qian, Janet L Williams, Diane D Lui, Eduardo Bruera, Sriram Yennurajalingam

Registry-linked trialAbstract read
In one paragraph

Article in Journal of palliative medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07421674 (Application Research of Hydromorphinone Sustained-release Tablets in the Treatment of Elderly Patients With Cancer Pain Accompanied by Renal Insufficiency), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07421674 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Application Research of Hydromorphinone Sustained-release Tablets in the Treatment of Elderly Patients With Cancer Pain Accompanied by Renal Insufficiency

Typeobservational_patient_registrySponsorTaian Cancer HospitalRan2026 to 2028Enrolled62ConditionsCancer Pain, Renal Insufficiency Chronic, Hydromorphone Use
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Assessment of Epidemiological Data and Surveillance in Korea Substance Use Research: Insights and Future Directions.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2024
    Review
  6. Review
  7. Opioid-induced Neurotoxicity in Patients with Cancer Pain.Current treatment options in oncology · 2023
    Review
  8. Identifying risk factors for opioid-induced neurotoxicity in cancer patients receiving oxycodone.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  9. Article
  10. Nicotine withdrawal as an unusual cause of terminal delirium.Canadian family physician Medecin de famille canadien · 2022
    Article
  11. Review
  12. Identification and management of opioid-induced neurotoxicity in older adults.Canadian family physician Medecin de famille canadien · 2022
    Article
  13. Article
  14. Review
  15. Prevalence and associated factors of orphan symptoms in advanced cancer patients: a multicenter observational study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Observational
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kyu-Hyoung LimDepartment of Internal Medicine, Kangwon National University School of Medicine, Chuncheon, Korea.
Nhu-Nhu NguyenDepartment of Palliative Care and Rehabilitation Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Yu QianDepartment of Internal Medicine, Kangwon National University School of Medicine, Chuncheon, Korea.
Janet L WilliamsDepartment of Palliative Care and Rehabilitation Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Diane D LuiDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Eduardo BrueraDepartment of Palliative Care and Rehabilitation Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Sriram YennurajalingamDepartment of Palliative Care and Rehabilitation Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.

Funding

A Combination Therapy for Cancer-Related Fatigue in Advanced Cancer PatientsR21NR016737 · NINR · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI YENNU, SRIRAM · 2018 to 2019
$372k
NINR NIH HHS R21 NR016737
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

InpatientsPalliative CareAdolescentAdultAgedAged, 80 and overAnalgesics, OpioidCancer PainFemaleHumansMaleMedical AuditMiddle AgedNeoplasmsNeurotoxicity SyndromesOutcome Assessment, Health CareAnalgesics, Opioiddeliriumdrowsinessmyoclonusopioidspalliative care

Identifiers

PMID30260731
PMCPMC6308282

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.