Evidence map›Paper›PMID 30260623›Full record

ArticleACS nano2018

Electrically Controllable Single-Point Covalent Functionalization of Spin-Cast Carbon-Nanotube Field-Effect Transistor Arrays.

Yoonhee Lee, Scott M Trocchia, Steven B Warren, Erik F Young, Sefi Vernick, Kenneth L Shepard

Abstract read
In one paragraph

Article in ACS nano, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yoonhee LeeDepartment of Electrical Engineering , Columbia University , New York , New York 10027 , United States.ORCID 0000-0003-0680-7668
Scott M TrocchiaDepartment of Electrical Engineering , Columbia University , New York , New York 10027 , United States.ORCID 0000-0002-7553-5208
Steven B WarrenPacific Biosciences , Menlo Park , California 94025 , United States.
Erik F YoungDepartment of Electrical Engineering , Columbia University , New York , New York 10027 , United States.
Sefi VernickAgricultural Research Organization, Volcani Center , Institute of Agricultural Engineering , Bet Dagan , Israel.
Kenneth L ShepardDepartment of Electrical Engineering , Columbia University , New York , New York 10027 , United States.

Funding

Translational CoreU19AI109761 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BARIC, RALPH S · 2014 to 2018
$32.6M
Single Molecule Real Time Electronic SequencingR01HG006882 · NHGRI · INTEL LABS · PI LEMAY, SERGE GUY, SHEPARD, KENNETH L · 2012 to 2015
$5.0M
Studies of Riboswitch-Mediated Transcriptional Control Using Single-Molecule FielR01GM107417 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI GONZALEZ, RUBEN L, NUCKOLLS, COLIN P · 2014 to 2017
$1.5M
NHGRI NIH HHS R01 HG006882NIAID NIH HHS U19 AI109761NIGMS NIH HHS R01 GM107417
6 · The paper itself

Abstract

Single-point-functionalized carbon-nanotube field-effect transistors (CNTFETs) have been used to sense conformational changes and binding events in protein and nucleic acid structures from intrinsic molecular charge. The key to utilizing these devices as single-molecule sensors is the ability to attach a single probe molecule to an individual device. In contrast, with noncovalent attachment approaches such as those based on van der Waals interactions, covalent attachment approaches generally deliver higher stability but have traditionally been more difficult to control, resulting in low yield. Here, we present a single-point-functionalization method for CNTFET arrays based on electrochemical control of a diazonium reaction to create sp

Indexed as

Electrochemical TechniquesTransistors, ElectronicDiazonium CompoundsDNADNA ProbesMolecular StructureNanotubes, CarbonNucleic Acid HybridizationDiazonium CompoundsDNADNA ProbesNanotubes, Carboncarbon nanotubeCNTFET arraydiazoniumDNA meltingsingle-point defectsmFETspin-castwafer scale

Identifiers

PMID30260623
PMCPMC6887518

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.