Evidence map›Paper›PMID 30260550›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2018

Relationship between thyroid function and elevated blood pressure in euthyroid adults.

Yeqing Gu, Lixiao Zheng, Qing Zhang, Li Liu, Ge Meng, Zhanxin Yao, Hongmei Wu, Yang Xia, Xue Bao, Hongbin Shi and 8 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 37 citations in OpenAlex.

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  10. Frontiers in nutrition · 2023
    Article
  11. Article
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  15. Article
  16. Article
  17. Relationship between thyroid function and elevated blood pressure in euthyroid adults.Journal of clinical hypertension (Greenwich, Conn.) · 2018
    Article
  18. Correlation Between Free Thyroxine Levels and Mortality in Hypertensive Patients.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 2 institutions in 1 country.

Yeqing GuNutritional Epidemiology Institute and School of Public Health, Tianjin Medical University, Tianjin, China.
Lixiao ZhengNutritional Epidemiology Institute and School of Public Health, Tianjin Medical University, Tianjin, China.
Qing ZhangHealth Management Centre, Tianjin Medical University General Hospital, Tianjin, China.
Li LiuHealth Management Centre, Tianjin Medical University General Hospital, Tianjin, China.
Ge MengNutritional Epidemiology Institute and School of Public Health, Tianjin Medical University, Tianjin, China.
Zhanxin YaoNutritional Epidemiology Institute and School of Public Health, Tianjin Medical University, Tianjin, China.
Hongmei WuNutritional Epidemiology Institute and School of Public Health, Tianjin Medical University, Tianjin, China.
Yang XiaNutritional Epidemiology Institute and School of Public Health, Tianjin Medical University, Tianjin, China.
Xue BaoNutritional Epidemiology Institute and School of Public Health, Tianjin Medical University, Tianjin, China.
Hongbin ShiHealth Management Centre, Tianjin Medical University General Hospital, Tianjin, China.
Honglei WangNutritional Epidemiology Institute and School of Public Health, Tianjin Medical University, Tianjin, China.
Haiyan XuNutritional Epidemiology Institute and School of Public Health, Tianjin Medical University, Tianjin, China.
Shaomei SunHealth Management Centre, Tianjin Medical University General Hospital, Tianjin, China.
Xing WangHealth Management Centre, Tianjin Medical University General Hospital, Tianjin, China.
Ming ZhouHealth Management Centre, Tianjin Medical University General Hospital, Tianjin, China.
Qiyu JiaHealth Management Centre, Tianjin Medical University General Hospital, Tianjin, China.
Kun SongHealth Management Centre, Tianjin Medical University General Hospital, Tianjin, China.
Kaijun NiuNutritional Epidemiology Institute and School of Public Health, Tianjin Medical University, Tianjin, China.ORCID 0000-0002-8772-2481
Tianjin Medical University · CNTianjin Medical University General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid hormones (THs) have profound effects on cardiovascular functions, suggesting that THs may contribute to the development of elevated blood pressure (BP). Few studies, however, have systematically assessed the relationship between THs and elevated BP. We therefore conducted a cross-sectional study to examine how serum THs concentrations are related to the prevalence of elevated BP in a euthyroid population. This study (n = 12 487) was performed in Tianjin, China. Serum free triiodothyronine (FT3), free thyroxine (FT4), and thyroid-stimulating hormone (TSH) levels were measured by chemiluminescence immunoassay. Elevated BP was defined according to the JNC 8 criteria. Analysis of covariance and multiple logistic regression models were used to assess the relationships between FT3, FT4, and TSH quartiles and elevated BP. The multivariable-adjusted odds ratios (95% confidence interval) of elevated BP for gradual increase in the FT3, FT4, and TSH quartiles, when compared to the lowest quartiles were 1.08 (0.97, 1.21), 1.24 (1.12, 1.39), and 1.32 (1.18, 1.47); 1.18 (1.06, 1.32), 1.18 (1.06, 1.31), and 1.24 (1.11, 1.38); 1.06 (0.96, 1.19), 1.06 (0.95, 1.18), and 1.03 (0.93, 1.15), respectively. Our study demonstrated that FT3 and FT4 are positively related to the prevalence of elevated BP in euthyroid adults, but no significant relationship was found between TSH and elevated BP.

Indexed as

AdultBlood Pressure DeterminationCardiovascular DiseasesChinaCross-Sectional StudiesFemaleHumansHypertensionMaleMiddle AgedPrevalenceProspective StudiesRisk FactorsThyroid Function TestsThyroid GlandThyroid HormonesThyroid HormonesThyrotropinThyroxineTriiodothyronineelevated blood pressureepidemiologyserum free thyroid hormonesthyroid functionthyroid-stimulating hormone

Identifiers

PMID30260550
PMCPMC8031048
OpenAlexW2890492934

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.