ArticleSchizophrenia bulletin2019
Working Memory Impairment Across Psychotic disorders.
Article in Schizophrenia bulletin, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 6 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
44 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Functional brain abnormalities of cognitive impairments in schizophrenia indicating higher integration of working memory than other domains.Molecular psychiatry · 2026Pooled it
- Relationships between cognition and daily functioning in adults with bipolar disorder: A systematic review and multilevel meta-analysis.Psychological bulletin · 2026Pooled it
- A Systematic Review and Meta-Analysis on Contrast Sensitivity in Schizophrenia.Schizophrenia bulletin · 2025Pooled it
- Pooled it
- Phonological working memory is adversely affected in adults with anorexia nervosa: a systematic literature review.Eating and weight disorders : EWD · 2022Pooled it
- Identifying regions in prefrontal cortex related to working memory improvement: A novel meta-analytic method using electric field modeling.Neuroscience and biobehavioral reviews · 2021Pooled it
- Apical integration theory provides a neural basis for understanding disorganization and consciousness in the schizophrenias.Current research in neurobiology · 2026Article
- Prior Trial Effects on Working Memory in Schizophrenia, Bipolar Disorder, and Healthy Control Individuals.JAMA psychiatry · 2026Article
- Prognostic Factors for Adulthood Psychosis in Adolescent Psychiatry Services: A Longitudinal Total Birth Cohort Study.Schizophrenia bulletin · 2026Article
- ERP Decoding Analysis of Visual Working Memory Processes in Schizophrenia.Alpha psychiatry · 2026Article
- Exploration of Factors That Affect Engagement With the Experience Sampling Method and Service Users' Experience of This Within the AVATAR2 Trial: Mixed Methods Study.JMIR formative research · 2025Article
- Opposite-Direction Spatial Working Memory Biases in People With Schizophrenia and Healthy Control Participants.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025Article
- Abnormalities in attention and working memory in schizophrenia: The hyperfocusing hypothesis.Current directions in psychological science · 2025Article
- Variations of blood D-serine and D-aspartate homeostasis track psychosis stages.Schizophrenia (Heidelberg, Germany) · 2024Article
- Dysfunctional Alpha Modulation as a Mechanism of Working Memory Impairment in Serious Mental Illness.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2024Article
- Leveraging ultra-high field (7T) MRI in psychiatric research.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Review
- Dissociable Contributions of Goal-Relevant Evidence and Goal-Irrelevant Familiarity to Individual and Developmental Differences in Conflict Recognition.Cognitive science · 2024Article
- Using Computational Phenotyping to Identify Divergent Strategies for Effort Allocation Across the Psychosis Spectrum.Schizophrenia bulletin · 2024Article
- Cognitive impairment as a predictor of long-term psychological distress in patients with polysubstance use disorders: a prospective longitudinal cohort study.BMC psychiatry · 2024Article
- Negative Symptoms and Their Associations With Other Clinical Variables and Working Memory Across the Schizophrenia Spectrum and Bipolar Disorder.Schizophrenia bulletin open · 2024Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
backgroundWorking memory (WM) has been a central focus of cognitive neuroscience research because WM is a resource that is involved in many different cognitive operations. The goal of this study was to evaluate the clinical utility of WM paradigms developed in the basic cognitive neuroscience literature, including methods designed to estimate storage capacity without contamination by lapses of attention.
methodsA total of 61 people with schizophrenia, 49 with schizoaffective disorder, 47 with bipolar disorder with psychosis, and 59 healthy volunteers were recruited. Participants received multiple WM tasks, including two versions each of a multiple Change Detection paradigm, a visual Change Localization paradigm, and a Running Span task.
resultsHealthy volunteers performed better than the combined patient group on the visual Change Localization and running span measures. The multiple Change Detection tasks provided mixed evidence about WM capacity reduction in the patient groups, but a mathematical model of performance suggested that the patient groups differed from controls in their rate of attention lapsing. The 3 patient groups performed similarly on the WM tasks. Capacity estimates from the Change Detection and Localization tasks showed significant correlations with functional capacity and functional outcome.
conclusionsThe patient groups generally performed in a similarly impaired fashion across tasks, suggesting that WM impairment and attention lapsing are general features of psychotic disorders. Capacity estimates from the Change Localization and Detection tasks were related to functional capacity and outcome, suggesting that these methods may be useful in a clinical context.
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