Evidence map›Paper›PMID 30260406›Full record

ArticleThe Journal of infectious diseases2019

Cutaneous Viral Infections Across 2 Anatomic Sites Among a Cohort of Patients Undergoing Skin Cancer Screening.

Dana E Rollison, Michael J Schell, Neil A Fenske, Basil Cherpelis, Jane L Messina, Anna R Giuliano, Pearlie K Epling-Burnette, Shalaka S Hampras, Rossybelle P Amorrortu, Juliana Balliu and 7 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Viruses in Skin Cancer (VIRUSCAN): Study Design and Baseline Characteristics of a Prospective Clinic-Based Cohort Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2020
    Article
  8. Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 2 countries.

Dana E RollisonDepartment of Cancer Epidemiology, Tampa, Florida.
Michael J SchellDepartment of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, Florida.
Neil A FenskeDepartment of Dermatology and Cutaneous Surgery, University of South Florida College of Medicine, Tampa, Florida.
Basil CherpelisDepartment of Dermatology and Cutaneous Surgery, University of South Florida College of Medicine, Tampa, Florida.
Jane L MessinaDepartment of Dermatology and Cutaneous Surgery, University of South Florida College of Medicine, Tampa, Florida.
Anna R GiulianoCenter for Immunization and Infection Research in Cancer, Tampa, Florida.
Pearlie K Epling-BurnetteDepartment of Immunology, Moffitt Cancer Center, Tampa, Florida.
Shalaka S HamprasDepartment of Cancer Epidemiology, Tampa, Florida.
Rossybelle P AmorrortuDepartment of Cancer Epidemiology, Tampa, Florida.
Juliana BalliuDepartment of Cancer Epidemiology, Tampa, Florida.
Laxmi VijayanDepartment of Cancer Epidemiology, Tampa, Florida.
Syeda Mahrukh Hussnain NaqviDepartment of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, Florida.
Yayi ZhaoDepartment of Cancer Epidemiology, Tampa, Florida.
Kaustubh ParabDepartment of Cancer Epidemiology, Tampa, Florida.
Sandrine McKay-ChopinInfections and Cancer Biology Group, International Agency for Research on Cancer, World Health Organization, Lyon, France.
Tarik GheitInfections and Cancer Biology Group, International Agency for Research on Cancer, World Health Organization, Lyon, France.
Massimo TommasinoInfections and Cancer Biology Group, International Agency for Research on Cancer, World Health Organization, Lyon, France.
Centre International de Recherche sur le Cancer · FRMoffitt Cancer Center · USFlorida College · USUniversity of South Florida · US

Funding

TRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI Christine O'Connell · 1998 to 2026
$93.5M
Prospective study of cutaneous viral infections and non-melanoma skin cancerR01CA177586 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI ROLLISON, DANA ELISE · 2014 to 2018
$3.4M
NCI NIH HHS P30 CA076292NCI NIH HHS R01 CA177586World Health Organization 001
6 · The paper itself

Abstract

backgroundFindings from previous studies of cutaneous human papillomavirus (cuHPV) infection and keratinocyte carcinomas have varied due to several factors, including use of different sample types for cuHPV DNA detection. Elucidating the relationship between cuHPV infection in eyebrow hairs (EBHs) and skin swabs (SSWs) is critical for advancing the design of future studies.

methodsDNA corresponding to 46 β-HPV and 52 γ-HPV types was measured in EBHs and SSWs obtained from 370 individuals undergoing routine skin cancer screening examinations.

resultsPrevalence of β-HPV/γ-HPV was 92%/84% and 73%/43% in SSWs and EBHs, respectively, with 71%/39% of patients testing positive for β-HPV/γ-HPV in both sample types. Number of cuHPV types detected and degree of infection were correlated across SSWs and EBHs. When the EBH was positive for a given β-HPV/γ-HPV type, the SSW was positive for that same type 81%/72% of the time.

conclusionsTesting SSWs captures more cuHPV infection than EBHs, with EBH infections usually representing a subset of SSW infections. The importance of optimizing sensitivity of cuHPV infection detection using SSWs vs specificity using EBHs (or a combination of the 2) will be ascertained in an ongoing cohort study investigating cuHPV associations with subsequent keratinocyte carcinomas.

Indexed as

AgedAged, 80 and overDiagnostic Tests, RoutineEyebrowsFemaleHumansMaleMiddle AgedPapillomaviridaePapillomavirus InfectionsPrevalenceSensitivity and SpecificitySkinSpecimen Handlingcutaneous human papillomavirusepidemiologyeyebrow hairspolyomavirusskin swabs

Identifiers

PMID30260406
PMCPMC6376905
OpenAlexW2893899953

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.