Evidence map›Paper›PMID 30260314›Full record

ArticleeLife2018

Phase transitioned nuclear Oskar promotes cell division of

Kathryn E Kistler, Tatjana Trcek, Thomas R Hurd, Ruoyu Chen, Feng-Xia Liang, Joseph Sall, Masato Kato, Ruth Lehmann

Open access · goldAbstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 107 citations in OpenAlex.

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  13. How germ granules promote germ cell fate.Nature reviews. Genetics · 2024
    Review
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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Kathryn E Kistler *Skirball Institute of Biomolecular Medicine, Howard Hughes Medical Institute, NYU School of Medicine, New York, United States.
Tatjana Trcek *Skirball Institute of Biomolecular Medicine, Howard Hughes Medical Institute, NYU School of Medicine, New York, United States.ORCID https://orcid.org/0000-0003-4405-8733
Thomas R HurdSkirball Institute of Biomolecular Medicine, Howard Hughes Medical Institute, NYU School of Medicine, New York, United States.
Ruoyu ChenSkirball Institute of Biomolecular Medicine, Howard Hughes Medical Institute, NYU School of Medicine, New York, United States.
Feng-Xia LiangDepartment of Cell Biology, NYU School of Medicine, New York, United States.
Joseph SallDART Microscopy Laboratory, NYU Langone Health, New York, United States.
Masato KatoDepartment of Biochemistry, University of Texas Southwestern Medical Center, Texas, United States.
Ruth LehmannSkirball Institute of Biomolecular Medicine, Howard Hughes Medical Institute, NYU School of Medicine, New York, United States.ORCID http://orcid.org/0000-0002-8454-5651
Howard Hughes Medical Institute · USNew York University · USThe University of Texas Southwestern Medical Center · US

Funding

Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ADRIANA HEGUY · 1985 to 2026
$83.1M
DROSOPHILA GENOMICS RESOURCE CENTERP40OD010949 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Andrew Zelhof · 2012 to 2026
$9.4M
Germ Cell Migration in Drosophila.R37HD041900 · NICHD · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI LEHMANN, RUTH · 2013 to 2021
$2.6M
Mechanisms of mRNA localization to Drosophila germ granulesR00HD088675 · NICHD · JOHNS HOPKINS UNIVERSITY · PI TRCEK, TATJANA · 2019 to 2021
$733k
Mechanisms of mRNA localization to Drosophila germ granulesK99HD088675 · NICHD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI TRCEK, TATJANA · 2017 to 2018
$239k
Eunice Kennedy Shriver National Institute of Child Health and Human Development K99HD088675Howard Hughes Medical InstituteNCI NIH HHS P30 CA016087NICHD NIH HHS K99 HD088675NICHD NIH HHS R00 HD088675NICHD NIH HHS R37 HD041900NIH HHS P40 OD010949
6 · The paper itself

Abstract

Germ granules are non-membranous ribonucleoprotein granules deemed the hubs for post-transcriptional gene regulation and functionally linked to germ cell fate across species. Little is known about the physical properties of germ granules and how these relate to germ cell function. Here we study two types of germ granules in the

Indexed as

AnimalsCell DifferentiationCell DivisionCell NucleusCytoplasmic GranulesDrosophila melanogasterDrosophila ProteinsEmbryonic DevelopmentGene Expression Regulation, DevelopmentalGerm CellsDrosophila Proteinsosk protein, Drosophilacell biologyD. melanogastergerm cellsgerm granulesmebraneless RNP granulesOskar proteinphase transition

Identifiers

PMID30260314
PMCPMC6191285
OpenAlexW2949552670

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.