Evidence map›Paper›PMID 30260210›Full record

ArticleAnalytical chemistry2018

Gas-Phase Ion/Ion Reactions Involving Tris-Phenanthroline Alkaline Earth Metal Complexes as Charge Inversion Reagents for the Identification of Fatty Acids.

Caitlin E Randolph, David J Foreman, Stella K Betancourt, Stephen J Blanksby, Scott A McLuckey

Abstract read
In one paragraph

Article in Analytical chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Review
  2. Analytical applications of gas-phase ion chemistry enabled by mass spectrometry.Analytical methods : advancing methods and applications · 2026
    Review
  3. Structural Elucidation of Phosphatidylcholines via Radical-Directed Dissociation of [M + CuJournal of the American Society for Mass Spectrometry · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Recent Advances in Gas-phase Ion/Ion Chemistry for Lipid Analysis.Trends in analytical chemistry : TRAC · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Caitlin E RandolphDepartment of Chemistry , Purdue University , West Lafayette , Indiana 47907-2084 , United States.
David J ForemanDepartment of Chemistry , Purdue University , West Lafayette , Indiana 47907-2084 , United States.
Stella K BetancourtDepartment of Chemistry , Purdue University , West Lafayette , Indiana 47907-2084 , United States.
Stephen J BlanksbyCentral Analytical Research Facility, Institute for Future Environments , Queensland University of Technology , Brisbane , Queensland 4000 , Australia.ORCID 0000-0002-8560-756X
Scott A McLuckeyDepartment of Chemistry , Purdue University , West Lafayette , Indiana 47907-2084 , United States.ORCID 0000-0002-1648-5570

Funding

Gas-phase Bio-conjugation in the Tandem Mass Spectrometry of Peptides, Proteins,R37GM045372 · NIGMS · PURDUE UNIVERSITY · PI MCLUCKEY, SCOTT A · 2014 to 2023
$3.1M
NIGMS NIH HHS R37 GM045372
6 · The paper itself

Abstract

Fatty acids (FA) play vital biological roles as energy sources, signaling molecules and key building blocks of complex lipids in cell membranes. Modifications to FA structure and composition are associated with the onset and progression of a number of chronic diseases. Consequently, the sensitive detection and unambiguous structure elucidation of FA is integral to the advancement of biomedical sciences. Recent advances in FA analysis have taken advantage of wet chemical derivatization to enhance detection and drive unique fragmentation in tandem mass spectrometry protocols. Here, we significantly further this approach through demonstrating gas-phase charge inversion of singly deprotonated FA ions, [M - H]

Indexed as

Coordination ComplexesCorn OilFatty Acids, UnsaturatedGasesLigandsMetals, Alkaline EarthMolecular StructurePhenanthrolinesCoordination ComplexesCorn OilFatty Acids, UnsaturatedGasesLigandsMetals, Alkaline EarthPhenanthrolines

Identifiers

PMID30260210
PMCPMC6688842

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.