ArticleObesity (Silver Spring, Md.)2018
Resistance Training Reduces Skeletal Muscle Work Efficiency in Weight-Reduced and Non-Weight-Reduced Subjects.
Article in Obesity (Silver Spring, Md.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Exercise for Weight Loss: Further Evaluating Energy Compensation with Exercise.Medicine and science in sports and exercise · 2020Trial
- The Physiology Of the WEight Reduced State (POWERS) study: assessing energy balance.International journal of obesity (2005) · 2026Article
- Can muscle avert GLP1R weight plateau and regain?Cell reports. Medicine · 2025Article
- Walking economy and exercise efficiency in successful weight loss maintainers.Physiology & behavior · 2025Article
- Thirty Obesity Myths, Misunderstandings, and/or Oversimplifications: An Obesity Medicine Association (OMA) Clinical Practice Statement (CPS) 2022.Obesity pillars · 2022Article
- Nutrition and physical activity: An Obesity Medicine Association (OMA) Clinical Practice Statement 2022.Obesity pillars · 2022Article
- Obesity history, physical exam, laboratory, body composition, and energy expenditure: An Obesity Medicine Association (OMA) Clinical Practice Statement (CPS) 2022.Obesity pillars · 2022Article
- Activation of Crtc2/Creb1 in skeletal muscle enhances weight loss during intermittent fasting.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021Article
- Challenges in tackling energy expenditure as obesity therapy: From preclinical models to clinical application.Molecular metabolism · 2021Review
- Reduced metabolic efficiency in sedentary eucaloric conditions predicts greater weight regain in adults with obesity following sustained weight loss.International journal of obesity (2005) · 2021Article
- The Role of Leptin in the Development of Energy Homeostatic Systems and the Maintenance of Body Weight.Frontiers in physiology · 2021Review
- Increasing Energy Flux to Maintain Diet-Induced Weight Loss.Nutrients · 2019Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
objectiveThe objective of this study is to determine whether resistance training is similarly effective in reducing skeletal muscle efficiency and increasing strength in weight-reduced and maximal weight subjects.
methodsThis study examined the effects of supervised resistance exercise on skeletal muscle in 14 individuals with overweight and obesity sustaining a 10% or greater weight loss for over 6 months and a phenotypically similar group of 15 subjects who had not reduced weight and were weight stable at their maximal lifetime body weight. We assessed skeletal muscle work efficiency and fuel utilization (bicycle ergometry), strength (dynamometry), body composition (dual energy x-ray absorptiometry), and resting energy expenditure (indirect calorimetry) before and after 12 weeks of thrice-weekly resistance training.
resultsNon-weight-reduced subjects were significantly (10%-20%) stronger before and after the intervention than reduced-weight subjects and gained significantly more fat-free mass with a greater decline in percentage of body fat than weight-reduced subjects. Resistance training resulted in similar significant decreases (~10%) in skeletal muscle work efficiency at low-level exercise and ~10% to 20% increases in leg strength in both weight-reduced and non-weight-reduced subjects.
conclusionsResistance training similarly increases muscle strength and decreases efficiency regardless of weight loss history. Increased resistance training could be an effective adjunct to reduced-weight maintenance therapy.
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Registered trials
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