Evidence map›Paper›PMID 30259422›Full record

ArticleMolecular diagnosis & therapy2018

Rapid Detection of the Macrolide Sensitivity of Pneumonia-Causing Mycoplasma pneumoniae Using Quenching Probe Polymerase Chain Reaction (GENECUBE

Yutaka Ito, Satoru Iwashima, Satoshi Hayano, Tomohiro Nishio, Ryosuke Shiozawa, Soichiro Yata, Toshiko Kubota, Akira Kubota, Keiichi Uemura

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Article in Molecular diagnosis & therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yutaka ItoDepartment of Pediatrics, Chutoen General Medical Center, Syoubugaike 1-1, Kakegawa, 436-8555, Japan.
Satoru IwashimaDepartment of Pediatrics, Chutoen General Medical Center, Syoubugaike 1-1, Kakegawa, 436-8555, Japan. iwashima3617@gmail.com.ORCID http://orcid.org/0000-0003-2713-321X
Satoshi HayanoDepartment of Pediatrics, Chutoen General Medical Center, Syoubugaike 1-1, Kakegawa, 436-8555, Japan.
Tomohiro NishioDepartment of Pediatrics, Chutoen General Medical Center, Syoubugaike 1-1, Kakegawa, 436-8555, Japan.
Ryosuke ShiozawaDepartment of Pediatrics, Chutoen General Medical Center, Syoubugaike 1-1, Kakegawa, 436-8555, Japan.
Soichiro YataDepartment of Pediatrics, Chutoen General Medical Center, Syoubugaike 1-1, Kakegawa, 436-8555, Japan.
Toshiko KubotaDepartment of Pediatrics, Chutoen General Medical Center, Syoubugaike 1-1, Kakegawa, 436-8555, Japan.
Akira KubotaDepartment of Pediatrics, Chutoen General Medical Center, Syoubugaike 1-1, Kakegawa, 436-8555, Japan.
Keiichi UemuraDepartment of Laboratory Center, Chutoen General Medical Center, Kakegawa, Japan.
Kagawa University · JPMie Chuo Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesMacrolide-resistant Mycoplasma pneumoniae (MR-MP) have been reported worldwide. Strategies for the treatment of MR-MP are a key focus of research. The GENECUBE

methodsThis was an observational retrospective study including 150 children with MP pneumonia. We used quenching probe polymerase chain reaction (Q-probe PCR) as implemented in the GENECUBE

resultsSelecting antibiotic treatment after Q-probe PCR significantly shortened the duration of fever compared to empirical antibiotic treatment (PCR First group, median: 6.0 days [n = 32]; Empirical T group, median: 7.5 days [n = 66]; p = 0.002). Comparison of macrolide sensitivity using Q-probe PCR and clinical diagnosis showed that the reliability of Q-probe PCR was nearly validated for macrolide sensitivity.

conclusionQ-probe PCR as implemented by GENECUBE

Indexed as

Anti-Bacterial AgentsHumansMacrolidesMycoplasma pneumoniaePneumoniaPolymerase Chain ReactionRetrospective StudiesAnti-Bacterial AgentsMacrolides

Identifiers

PMID30259422
OpenAlexW2894064540

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.