ReviewBiogerontology2018
Age-related changes in skeletal muscle: changes to life-style as a therapy.
Review in Biogerontology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
104 citing papers in PubMed, 1 synthesis or guideline pooled it, 196 citations in OpenAlex.
- Chronic Effects of Altering Resistance Training Set Configurations Using Cluster Sets: A Systematic Review and Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2021Pooled it
- Trial
- Peripheral Blood T Cell Gene Expression Responses to Exercise and HMB in Sarcopenia.Nutrients · 2021Trial
- Nutrient patterns and the skeletal muscle mass index among Polish women: a cross-sectional study.Scientific reports · 2019Trial
- Neonatal muscle-derived extracellular vesicles containing miR-542-3p rejuvenate aged skeletal muscle via a functional microneedle patch.Bioactive materials · 2026Article
- Preserved mitochondrial respiration in presence of oxidative stress and reduced mitochondrial mass after 10-day bed rest in older adults.The Journal of physiology · 2026Article
- Cultural Adaptation and Structural Validation of the Short-Form Örebro Musculoskeletal Screening Questionnaire in Peruvian Nurses with Musculoskeletal Symptoms.Healthcare (Basel, Switzerland) · 2026Article
- Reference Intervals and Prediction Equation for Sustained Maximal Inspiratory Pressure in Healthy Adults.Cureus · 2026Article
- A High-Fat/High-Sugar Diet Is Associated with Reduced Motor Unit Number and Neuromuscular Dysfunction in Late-Middle-Aged Female Rats: A Pilot Study.Life (Basel, Switzerland) · 2026Article
- Functional Sensorimotor-Based Training for Balance and Gait Enhancement in Sedentary Older Women: A Randomized Clinical Trial.Health science reports · 2026Article
- Temporal Muscle Thickness Is a Prognostic Factor for Neurological Recovery After Surgery for Chronic Subdural Hematoma.Diagnostics (Basel, Switzerland) · 2026Article
- Age-Related Structural-Functional Discrepancy in Muscle Indicators Among Rural Korean Older Women.Journal of aging research · 2026Article
- Effects of 12 weeks resistance training on muscle quality and physical performance in normal-weight and obese older women.Frontiers in physiology · 2026Article
- From muscle to brain: the mediating effect of vitamin D in the relationship between muscle loss and cognitive function in Alzheimer's disease.Frontiers in aging neuroscience · 2026Article
- Angiotensin-Converting Enzyme Inhibitors and Metabolic Aging: A Drosophila Perspective.Biomolecules · 2025Review
- Association Between Muscle Quality Assessed by the 5-Repetition Sit-to-Stand Test and Falls in Community-Dwelling Older Adults in Japan: A Cross-Sectional Study.Geriatrics (Basel, Switzerland) · 2025Article
- Skeletal Muscle as a Mediator of Interorgan Crosstalk During Exercise: Implications for Aging and Obesity.Circulation research · 2025Review
- Melatonin protects against sarcopenia in middle-aged mice.Histology and histopathology · 2025Article
- Are There Differences in Postural Control and Muscular Activity in Individuals with COPD and with and Without Sarcopenia?Advances in respiratory medicine · 2025Article
- Muscle Organoid and Assembloid Systems.Advances in experimental medicine and biology · 2025Review
44 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
As we age, there is an age-related loss in skeletal muscle mass and strength, known as sarcopenia. Sarcopenia results in a decrease in mobility and independence, as well as an increase in the risk of other morbidities and mortality. Sarcopenia is therefore a major socio-economical problem. The mechanisms behind sarcopenia are unclear and it is likely that it is a multifactorial condition with changes in numerous important mechanisms all contributing to the structural and functional deterioration. Here, we review the major proposed changes which occur in skeletal muscle during ageing and highlight evidence for changes in physical activity and nutrition as therapeutic approaches to combat age-related skeletal muscle wasting.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.