Evidence map›Paper›PMID 30259284›Full record

Trial reportBreast cancer research and treatment2019

Dietary intervention among breast cancer survivors increased adherence to a Mediterranean-style, anti-inflammatory dietary pattern: the Rx for Better Breast Health Randomized Controlled Trial.

Krystle E Zuniga, Dorothy Long Parma, Edgar Muñoz, Mackenzie Spaniol, Michael Wargovich, Amelie G Ramirez

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Breast cancer research and treatment, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
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  5. Mediterranean Diet and its Benefits on Health and Mental Health: A Literature Review.Clinical practice and epidemiology in mental health : CP & EMH · 2020
    Pooled it
  6. Dietary interventions for adult cancer survivors.The Cochrane database of systematic reviews · 2019
    Pooled it
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  8. Effect of an anti-inflammatory dietary intervention on quality of life among breast cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
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  11. Diallyl disulfide in oncotherapy: molecular mechanisms and therapeutic potentials.Apoptosis : an international journal on programmed cell death · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Krystle E ZunigaSchool of Family and Consumer Sciences, Nutrition and Foods, Texas State University, San Marcos, USA. k_z17@txstate.edu.ORCID http://orcid.org/0000-0002-3857-155X
Dorothy Long ParmaDepartment of Epidemiology and Biostatistics, Institute for Health Promotion Research, UT Health San Antonio, San Antonio, USA.
Edgar MuñozDepartment of Epidemiology and Biostatistics, Institute for Health Promotion Research, UT Health San Antonio, San Antonio, USA.
Mackenzie SpaniolDepartment of Epidemiology and Biostatistics, Institute for Health Promotion Research, UT Health San Antonio, San Antonio, USA.
Michael WargovichDepartment of Molecular Medicine, UT Health San Antonio, San Antonio, USA.
Amelie G RamirezDepartment of Epidemiology and Biostatistics, Institute for Health Promotion Research, UT Health San Antonio, San Antonio, USA.

Funding

TISSUE CULTURE---COREP30CA054174 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Lei Zheng · 1991 to 2026
$59.1M
Training ProgramU54CA153511 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI RAMIREZ, AMELIE G · 2010 to 2015
$6.2M
NCI NIH HHS P30 CA054174NCI NIH HHS U54 CA153511Redes en Accion: The National Latino Cancer Research Network U54CA153511Susan G. Komen SAB08-0005UT Health San Antonio Mays Cancer Center through the NCI Cancer Center Support Grant P30 CA054174
6 · The paper itself

Abstract

purposeThe goal of this education and culinary-based dietary intervention was to increase adherence to a Mediterranean-style, anti-inflammatory dietary pattern in breast cancer survivors (BCS) by promoting the consumption of anti-inflammatory foods, herbs, and spices.

methodsOverweight and obese, early-stage, BCS were randomized to the Intervention (n = 76) or Control (n = 77). The 6-month intervention included monthly nutrition and cooking workshops, Motivational Interviewing telephone calls, and individualized newsletters. Control participants received monthly informational brochures and no navigational services. Dietary intakes were collected via questionnaire and 3-day food records at baseline and 6 months.

resultsOne hundred twenty-five BCS (n = 60 I; n = 65 C) completed post-testing (81.7%) and were included in analyses. Adherence to Mediterranean diet guidelines significantly increased in the intervention group, but not in the control group (+ 22.5% vs. + 2.7%, P < 0.001). Upon further analysis of adherence to individual dietary guidelines, the intervention group significantly improved adherence to only three guidelines: consuming ≥ 3 servings of fish or shellfish/week, reducing red meat intake to < 1 serving/day, and limiting consumption of commercial sweets and baked goods to < 3 times/week. The intervention arm increased the use of spices and herbs compared to control (+ 146.2% vs. +33.3%, P < 0.001), including significantly more frequent consumption of cinnamon, turmeric, garlic, ginger, black pepper, and rosemary.

conclusionAn education and culinary-based intervention in BCS successfully increased adherence to a more Mediterranean-style, anti-inflammatory dietary pattern by increasing the consumption of anti-inflammatory foods, spices, and herbs and decreasing the consumption of pro-inflammatory foods.

Indexed as

Breast NeoplasmsCancer SurvivorsDiet, MediterraneanPatient ComplianceAgedFemaleHealth Knowledge, Attitudes, PracticeHumansInflammationMiddle AgedObesityPatient Education as TopicSpicesAnti-inflammatoryBreast cancer survivorDietMediterranean dietSurvivorship

Identifiers

PMID30259284
PMCPMC6387648

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.