ArticleClinical rheumatology2019
Increasing incidence and shifting profile of idiopathic inflammatory rheumatic diseases in adults during this millennium.
Article in Clinical rheumatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 36 citations in OpenAlex.
- Psoriatic arthritis patients have increased morbidity already at the time of diagnosis: a case-control study.Rheumatology international · 2026Article
- Visual clues - dermatological manifestations of sexually transmitted infections in men.Nature reviews. Urology · 2026Review
- The apprehension of seronegative rheumatoid arthritis.Nature reviews. Rheumatology · 2025Article
- Evidence for Exercise Therapy in Elderly Patients with Rheumatoid Arthritis.Juntendo medical journal · 2025Article
- Pain management, prolonged opioid use, initiated anti-rheumatic treatment and psychiatric morbidity in new-onset psoriatic arthritis.Rheumatology advances in practice · 2025Article
- Enteric Infection-Associated Reactive Arthritis: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2024Review
- Rheumatoid arthritis epidemiology: a nationwide study in Poland.Rheumatology international · 2024Article
- Review
- When Autoantibodies Are Missing: The Challenge of Seronegative Rheumatoid Arthritis.Antibodies (Basel, Switzerland) · 2023Review
- Incidence of seropositive rheumatoid arthritis in population-based studies in Northern Savo, Finland, during 1980-2020.Rheumatology international · 2023Article
- Impact of TNF inhibitor medication on working ability in axial spondyloarthritis: an observational national registry-based cohort study.Rheumatology advances in practice · 2023Article
- Increasing incidence of autoantibody-negative RA is replicated and is partly explained by an aging population.Annals of the rheumatic diseases · 2022Article
- Very low prevalence of ultrasound-detected tenosynovial abnormalities in healthy subjects throughout the age range: OMERACT ultrasound minimal disease study.Annals of the rheumatic diseases · 2022Article
- Is seronegative rheumatoid arthritis true rheumatoid arthritis? A nationwide cohort study.Rheumatology (Oxford, England) · 2021Article
- Fibromyalgia interferes with disease activity and biological therapy response in inflammatory rheumatic diseases.Rheumatology international · 2020Review
- Is the epidemiology of rheumatoid arthritis changing? Results from a population-based incidence study, 1985-2014.Annals of the rheumatic diseases · 2020Article
- Link Between Synovial and Myocardial Inflammation: Conceptual Framework to Explain the Pathogenesis of Heart Failure with Preserved Ejection Fraction in Patients with Systemic Rheumatic Diseases.Cardiac failure review · 2020Review
- First-year drug therapy of new-onset rheumatoid and undifferentiated arthritis: a nationwide register-based study.BMC rheumatology · 2020Article
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 1 country.
Funding
Abstract
To explore the trends in the incidence of idiopathic inflammatory rheumatic diseases (IIRDs) after the turn of the millennium. From a nationwide register maintained by the Social Insurance Institution of Finland, we collected all adult patients with IIRDs granted a new special reimbursement for anti-rheumatic drugs between 2000 and 2014. Temporal trends in the incidences of various IIRDs were estimated in three 5-year intervals. A total of 58,405 adult patients were identified. Between 2000-2004 and 2010-2014, the age-adjusted incidence rate of IIRDs increased from 114 to 116/100000 [incidence rate ratio (IRR) 1.03 (95% CI 1.01 to 1.06)] in women and from 67 to 69/100,000 [IRR 1.10 (95% CI 1.06-1.14)] in men. The incidence of seropositive rheumatoid arthritis (RA) remained stable while that of seronegative RA decreased. For other diagnoses, the incidences either increased (unspecified arthritis, psoriatic arthritis, spondyloarthritis), remained stable (reactive arthritis), or decreased (SLE and the group of diseases with the ICD-10 code M35). The gender difference in spondyloarthritis leveled as the incidence in women increased at a higher rate than in men. Mean age at IIRD diagnosis decreased among women. The total age-adjusted incidence of IIRDs has gradually increased, due to the increase in unspecified arthritis, psoriatic arthritis, and spondyloarthritis. This, in addition to the ascending number of individuals at risk in the population, translates into a growing burden to the health care system.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.