Evidence map›Paper›PMID 30259199›Full record

ReviewCurrent cardiology reports2018

Skeletal Muscle Myopathy in Heart Failure: the Role of Ejection Fraction.

Mara Paneroni, Evasio Pasini, Laura Comini, Michele Vitacca, Federico Schena, Simonetta Scalvini, Massimo Venturelli

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current cardiology reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Mara PaneroniIstituti Clinici Scientifici Maugeri, IRCCS, Pavia, Italy.
Evasio PasiniIstituti Clinici Scientifici Maugeri, IRCCS, Pavia, Italy.
Laura CominiIstituti Clinici Scientifici Maugeri, IRCCS, Pavia, Italy.
Michele VitaccaIstituti Clinici Scientifici Maugeri, IRCCS, Pavia, Italy.
Federico SchenaDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Via Casorati 43, 37100, Verona, Italy.
Simonetta ScalviniIstituti Clinici Scientifici Maugeri, IRCCS, Pavia, Italy.
Massimo VenturelliDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Via Casorati 43, 37100, Verona, Italy. Massimo.venturelli@univr.it.
Istituti Clinici Scientifici Maugeri · ITUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThis review summarizes: (1) the structural and functional features coupled with pathophysiological factors responsible of skeletal muscle myopathy (SMM) in both heart failure with reduced (HFrEF) and preserved (HFpEF) ejection fraction and (2) the role of exercise as treatment of SMM in these HF-related phenotypes. RECENT

findingsThe recent literature showed two main phenotypes of heart failure (HF): (1) HFrEF primarily due to a systolic dysfunction of the left ventricle and (2) HFpEF, mainly related to a diastolic dysfunction. Exercise intolerance is one of most disabling symptoms of HF and it is shown that persists after the normalization of the central hemodynamic impairments by therapy and/or cardiac surgery including heart transplant. A specific skeletal muscle myopathy (SMM) has been defined as one of the main causes of exercise intolerance in HF. The SMM has been well described in the last 20 years in the HFrEF; on the contrary, few studies are available in HFpEF. Recent evidences have revealed that exercise training counteracts HF-related SMM and in turn ameliorates exercise intolerance.

Indexed as

ExerciseStroke VolumeExercise ToleranceHeart FailureHeart TransplantationHemodynamicsHumansMuscle, SkeletalMuscular DiseasesOxygen ConsumptionRandomized Controlled Trials as TopicExercise trainingHeart failureHypermetabolic syndromeInflammationPreserved ejection fractionReduced ejection fraction

Identifiers

PMID30259199
OpenAlexW2893512763

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.