Evidence map›Paper›PMID 30259105›Full record

ArticleActa neuropathologica2018

cIMPACT-NOW update 3: recommended diagnostic criteria for "Diffuse astrocytic glioma, IDH-wildtype, with molecular features of glioblastoma, WHO grade IV".

Daniel J Brat, Kenneth Aldape, Howard Colman, Eric C Holland, David N Louis, Robert B Jenkins, B K Kleinschmidt-DeMasters, Arie Perry, Guido Reifenberger, Roger Stupp and 2 more

Abstract readLetter
In one paragraph

Article in Acta neuropathologica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 487 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
487citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

487 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. Pooled it
  4. Imaging features associated with H3 K27-altered and H3 G34-mutant gliomas: a narrative systematic review.Cancer imaging : the official publication of the International Cancer Imaging Society · 2022
    Pooled it
  5. Dual Immune Check Point Blockade inJournal of clinical oncology : official journal of the American Society of Clinical Oncology · 2025
    Trial
  6. Trial
  7. Response Rate and Molecular Correlates to Encorafenib and Binimetinib in BRAF-V600E Mutant High-Grade Glioma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024
    Trial
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Observational

427 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Daniel J BratDepartment of Pathology, Robert H. Lurie Cancer Center, Northwestern University Feinberg School of Medicine, Ward Building, 3-140, 303 E. Chicago Ave, Chicago, IL, 60611, USA. Daniel.brat@northwestern.edu.
Kenneth AldapeLaboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
Howard ColmanDepartment of Neurosurgery, Huntsman Cancer Center, University of Utah, Salt Lake City, UT, USA.
Eric C HollandDepartment of Neurosurgery, Fred Hutchinson Cancer Center, University of Washington, Seattle, WA, USA.
David N LouisDepartment of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Robert B JenkinsDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
B K Kleinschmidt-DeMastersDepartment of Pathology, University of Colorado School of Medicine, Aurora, CO, USA.
Arie PerryDepartment of Pathology, University of California San Francisco, San Francisco, CA, USA.
Guido ReifenbergerDepartment of Neuropathology, Heinrich Heine University, Düsseldorf, Germany.
Roger StuppMalnati Brain Tumor Institute, Robert H. Lurie Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Andreas von DeimlingDepartment of Neuropathology, Institute of Pathology, University of Heidelberg, Heidelberg, Germany.
Michael WellerDepartment of Neurology, University Hospital and University of Zurich, Zurich, Switzerland.

Funding

Genomic Biomarkers of CancerZIABC011850 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI ALDAPE, KENNETH · 2019 to 2025
$5.1M
Molecular Target Variation Across Environments and at Margins of GlioblastomaR01CA176659 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BRAT, DANIEL J, HADJIPANAYIS, CONSTANTINOS GEORGE · 2013 to 2017
$2.3M
NCI NIH HHS R01 CA176659
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Central Nervous System NeoplasmsErbB ReceptorsGlioblastomaHumansIsocitrate DehydrogenaseMutationPromoter Regions, GeneticTelomeraseWorld Health OrganizationEGFR protein, humanErbB ReceptorsIsocitrate DehydrogenaseTelomeraseTERT protein, human

Identifiers

PMID30259105
PMCPMC6204285

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.