Evidence map›Paper›PMID 30259089›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2019

Five-year clinical outcomes of combined phacoemulsification and trabectome surgery at a single glaucoma center.

Hamed Esfandiari, Priyal Shah, Pooya Torkian, Ian P Conner, Joel S Schuman, Kiana Hassanpour, Nils A Loewen

Abstract read
In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Minimally Invasive Glaucoma Surgery: Where Is the Evidence?Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)
    Pooled it
  2. Article
  3. Observational
  4. Article
  5. [Visual field prediction based on temporal-spatial feature learning].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2024
    Article
  6. Review
  7. IOP-lowering and drug-sparing effects of trabectome surgery with or without cyclodialysis ab interno.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Characteristics of glaucoma patients with intraocular pressure elevation early after trabectome surgery.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Long-term clinical results of trabectome surgery in patients with open-angle glaucoma.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020
    Article
  18. Article
  19. Can a contact lens sensor predict the success of trabectome surgery?Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hamed EsfandiariDepartment of Ophthalmology, School of Medicine, University of Pittsburgh, 203 Lothrop St, Suite 819, Pittsburgh, PA, 15213, USA.
Priyal ShahDepartment of Ophthalmology, School of Medicine, University of Pittsburgh, 203 Lothrop St, Suite 819, Pittsburgh, PA, 15213, USA.
Pooya TorkianOphthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Ian P ConnerDepartment of Ophthalmology, School of Medicine, University of Pittsburgh, 203 Lothrop St, Suite 819, Pittsburgh, PA, 15213, USA.
Joel S SchumanDepartment of Ophthalmology, School of Medicine, New York University, NY, New York City, USA.
Kiana HassanpourOphthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Nils A LoewenDepartment of Ophthalmology, School of Medicine, University of Pittsburgh, 203 Lothrop St, Suite 819, Pittsburgh, PA, 15213, USA. loewen.nils@gmail.com.ORCID http://orcid.org/0000-0001-7167-1213

Funding

Virus Production and Manipulation of Protein/Gene Expression ModuleP30EY008098 · NEI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Ethan A Rossi · 1989 to 2026
$17.8M
NEI NIH HHS P30 EY008098NIH CORE Grant P30 EY08098
6 · The paper itself

Abstract

purposeTo analyze the 5-year results of trabectome ab interno trabeculectomy of a single glaucoma center.

methodIn this retrospective interventional single-center case series, data of 93 patients undergoing ab interno trabeculotomy between September 2010, and December 2012 were included. Kaplan-Meier analysis was performed using success criteria defined as postoperative intraocular pressure (IOP) ≤ 21 mmHg, and > 20% reduction from preoperative IOP, and no need for further glaucoma surgery. Risk factors for failure were identified using Cox proportional hazards ratio (HR).

resultsThe retention rate for 5-year follow-up was 66%. The cumulative probability of success at 1, 2, 3, 4, and 5 years was 82.6%, 76.7%, 73.9%, 72.3%, and 67.5%. Risk factors for failure were lower baseline IOP (HR = 0.27, P = 0.001), younger age (HR = 0.25, P = 0.02), and higher central corneal thickness (HR = 0.18, P = 0.01). Exfoliative glaucoma was associated with a higher success rate (HR = 0.39, P = 0.02). IOP was decreased significantly from 20.0 ± 5.6 mmHg at baseline to 15.6 ± 4.6 mmHg at 5-year follow-up (P = 0.001). The baseline number of glaucoma medications was 1.8 ± 1.2, which decreased to 1.0 ± 1.2 medications at 5 years.

conclusionTrabectome surgery was associated with a good long-term efficacy and safety profile in this single-center case series with a high retention rate.

Indexed as

AgedCataractFemaleFollow-Up StudiesGlaucoma, Open-AngleHumansIntraocular PressureMalePhacoemulsificationTime FactorsTrabeculectomyTreatment OutcomeVisual AcuityAb interno trabeculectomyLong-term outcomesMicroinvasive glaucoma surgeriesMIGSTrabectome surgery

Identifiers

PMID30259089
PMCPMC7798351

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.