Evidence map›Paper›PMID 30258915›Full record

ArticleGenes & diseases2017

Seeking the "mother of blood" from human pluripotent stem cells: Are we there yet?

Fei Li

Abstract read
In one paragraph

Article in Genes & diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Fei LiThe Editorial Office of Genes & Diseases, Chongqing Medical University, Chongqing, 400046, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Induced pluripotent stem cells (iPSCs) hold great promise for the treatment of human diseases, including the failure of bone marrow. Incremental progress across the past three and half decades has brought us closer to making hematopoietic stem cells from iPSCs clinical solutions. A recent innovative two-step differentiation approach successfully generated transplantable HSCs from iPSC sources. For clinical translation, the long-term safety of these gene-altered HSCs must be determined.

Indexed as

Hemaotpoietic stem cellsHuman iPSCLentiviral transductionTeratomaTranscription factorsXeno-transplantation

Identifiers

PMID30258915
PMCPMC6146206

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.