Evidence map›Paper›PMID 30258882›Full record

ReviewGenes & diseases2016

Verena Staedtke, Nicholas J Roberts, Ren-Yuan Bai, Shibin Zhou

Open access · diamondAbstract readReview
In one paragraph

Review in Genes & diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 1 synthesis or guideline pooled it, 132 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Programmable genetic control of tumor-colonizingbioRxiv : the preprint server for biology · 2026
    Article
  5. Review
  6. Engineered probioticScience advances · 2026
    Article
  7. Toward development of soil-derivedBiodesign research · 2026
    Article
  8. Metabolic Gadolinium Labeling ofBiomaterials research · 2026
    Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Designing live bacterial therapeutics for cancer.Advanced drug delivery reviews · 2025
    Review
  17. Article
  18. Review
  19. Transforming bacterial pathogens into wonder tools in cancer immunotherapy.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  20. Review

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Verena StaedtkeLudwig Center for Cancer Genetics and Therapeutics, The Johns Hopkins Sidney Kimmel Cancer Center, Baltimore, MD 21287, USA.
Nicholas J RobertsLudwig Center for Cancer Genetics and Therapeutics, The Johns Hopkins Sidney Kimmel Cancer Center, Baltimore, MD 21287, USA.
Ren-Yuan BaiDepartment of Neurosurgery, The Johns Hopkins Medical Institutes, Baltimore, MD 21231, USA.
Shibin ZhouLudwig Center for Cancer Genetics and Therapeutics, The Johns Hopkins Sidney Kimmel Cancer Center, Baltimore, MD 21287, USA.
Johns Hopkins University · USSidney Kimmel Cancer Center · US

Funding

Tumor Antigens for Individual Signatures and TherapyP50CA062924 · NCI · JOHNS HOPKINS UNIVERSITY · PI LENNON, ANNE MARIE · 1993 to 2022
$54.6M
Integrative Analyses to Identify Pancreatic Cancer Susceptibility GenesK99CA190889 · NCI · JOHNS HOPKINS UNIVERSITY · PI ROBERTS, NICHOLAS JASON · 2015 to 2016
$172k
Identify OTX2-interacting proteins repressing differentiation in medulloblastomaR03CA178118 · NCI · JOHNS HOPKINS UNIVERSITY · PI BAI, RENYUAN · 2014 to 2015
$162k
NCI NIH HHS K99 CA190889NCI NIH HHS P50 CA062924NCI NIH HHS R03 CA178118
6 · The paper itself

Abstract

The attenuated anaerobic bacterium

Indexed as

BacteriaBacterial cancer therapyCancerClostridiumClostridium novyi-NTHypoxiaImmunotherapy

Identifiers

PMID30258882
PMCPMC6150096
OpenAlexW2263366764

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.