Evidence map›Paper›PMID 30258724›Full record

ArticlePeerJ2018

Discovery of two skin-derived dermaseptins and design of a TAT-fusion analogue with broad-spectrum antimicrobial activity and low cytotoxicity on healthy cells.

Haohao Zhu, Xiyan Ding, Wei Li, Tulin Lu, Chengbang Ma, Xinping Xi, Lei Wang, Mei Zhou, Roberta Burden, Tianbao Chen

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
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  6. Review
  7. Review
  8. Diversity of Antimicrobial Peptides in Silkworm.Life (Basel, Switzerland) · 2023
    Review
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  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Haohao Zhu *School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.
Xiyan Ding *School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.
Wei LiSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.
Tulin LuSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.
Chengbang MaSchool of Pharmacy, The Queen's University Belfast, Belfast, United Kingdom.
Xinping XiSchool of Pharmacy, The Queen's University Belfast, Belfast, United Kingdom.
Lei WangSchool of Pharmacy, The Queen's University Belfast, Belfast, United Kingdom.
Mei ZhouSchool of Pharmacy, The Queen's University Belfast, Belfast, United Kingdom.
Roberta BurdenSchool of Pharmacy, The Queen's University Belfast, Belfast, United Kingdom.
Tianbao ChenSchool of Pharmacy, The Queen's University Belfast, Belfast, United Kingdom.
Queen's University Belfast · GBNanjing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two novel peptides belonging to the dermaseptin family, namely DRS-CA-1 and DRS-DU-1, were encoded from cDNA libraries derived from the skin secretions of

Indexed as

Antimicrobial peptideCell viability.DermaseptinMolecular cloningSkin secretion

Identifiers

PMID30258724
PMCPMC6151122
OpenAlexW2891277755

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.