ArticleBiomedical optics express2018
Beyond backscattering: optical neuroimaging by BRAD.
Article in Biomedical optics express, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 27 citations in OpenAlex.
- Accurate flow speed measurement through correlation ratios using a mode-selective photonic lantern in optical coherence tomography.Biomedical optics express · 2025Article
- Speckle contrast reduction through the use of a modally-specific photonic lantern for optical coherence tomography.Biomedical optics express · 2023Article
- Ultra-parallel label-free optophysiology of neural activity.iScience · 2022Article
- Simultaneous directional full-field OCT using path-length and carrier multiplexing.Optics express · 2021Article
- All-fiber few-mode optical coherence tomography using a modally-specific photonic lantern.Biomedical optics express · 2021Article
- Reconstruction of angle-resolved backscattering through a multimode fiber for cell nuclei and particle size determination.APL photonics · 2020Article
- Article
- Three-dimensional visualization of opacifications in the murine crystalline lens by in vivo optical coherence tomography.Biomedical optics express · 2020Article
- Scattering Angle Resolved Optical Coherence Tomography Detects Early Changes in 3xTg Alzheimer's Disease Mouse Model.Translational vision science & technology · 2020Article
- Optical fiber bundles: Ultra-slim light field imaging probes.Science advances · 2019Article
- Angular range, sampling and noise considerations for inverse light scattering analysis of nuclear morphology.Journal of biophotonics · 2019Article
- Assessment of pathological features in Alzheimer's disease brain tissue with a large field-of-view visible-light optical coherence microscope.Neurophotonics · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 3 institutions in 1 country.
Funding
Abstract
Optical coherence tomography (OCT) is a powerful technology for rapid volumetric imaging in biomedicine. The bright field imaging approach of conventional OCT systems is based on the detection of directly backscattered light, thereby waiving the wealth of information contained in the angular scattering distribution. Here we demonstrate that the unique features of few-mode fibers (FMF) enable simultaneous bright and dark field (BRAD) imaging for OCT. As backscattered light is picked up by the different modes of a FMF depending upon the angular scattering pattern, we obtain access to the directional scattering signatures of different tissues by decoupling illumination and detection paths. We exploit the distinct modal propagation properties of the FMF in concert with the long coherence lengths provided by modern wavelength-swept lasers to achieve multiplexing of the different modal responses into a combined OCT tomogram. We demonstrate BRAD sensing for distinguishing differently sized microparticles and showcase the performance of BRAD-OCT imaging with enhanced contrast for ex vivo tumorous tissue in glioblastoma and neuritic plaques in Alzheimer's disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.