ArticleThe open ophthalmology journal2018
Clinical Characteristics, Treatment Outcomes and Predictive Factors in Optic Neuritis.
Article in The open ophthalmology journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- AQP4-IgG and MOG-IgG Related Optic Neuritis-Prevalence, Optical Coherence Tomography Findings, and Visual Outcomes: A Systematic Review and Meta-Analysis.Frontiers in neurology · 2020Pooled it
- Bilateral immune-mediated optic neuritis following HPV vaccination in an adolescent: diagnostic challenges and a rare clinical presentation.BMC neurology · 2026Article
- Demographic and Epidemiological Profile of Optic Neuritis in Colombia: A Retrospective Study Using Data from the Comprehensive Information System for Social Protection.Neuro-ophthalmology (Aeolus Press) · 2026Article
- Neuroophthalmological evaluation in primary inflammatory demyelinating diseases with special reference to optic neuritis: A prospective study.Journal of family medicine and primary care · 2025Article
- Visual Functions in Patients with Optic Neuritis Pre and Post Treatment: An Observational Study.JNMA; journal of the Nepal Medical Association · 2025Observational
- Clinical profile and challenges faced in the management of optic neuritis: the Indian scenario.International ophthalmology · 2024Article
- A 10-Year Single-Center Study of the Clinical Characteristics of Optic Neuritis-Related NMOSD, MS, and Double Seronegative Optic Neuritis, Together with Factors Predicting Visual Outcomes.Vision (Basel, Switzerland) · 2023Article
- Update on Optic Neuritis: An International View.Neuro-ophthalmology (Aeolus Press) · 2022Review
- Approach to optic neuritis: An update.Indian journal of ophthalmology · 2021Review
- Prognostic Factors for Visual Outcomes Following the First Episode of NMOSD-Related Optic Neuritis in Affected Eyes.Clinical ophthalmology (Auckland, N.Z.) · 2020Article
- Etiologies of Acute Optic Neuritis in Thailand: An Observational Study of 171 Patients.Clinical ophthalmology (Auckland, N.Z.) · 2020Article
- Prognostic Factors for Recovery of Vision in Canine Optic Neuritis of Unknown Etiology: 26 Dogs (2003-2018).Frontiers in veterinary science · 2019Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe causes, clinical presentations and treatment outcomes of optic neuritis are distinct among different populations. Early diagnosis based on clinical presentations plays an important role in treating optic neuritis patients.
objectiveThe study aimed to determine clinical characteristics, treatment outcomes and predictive factors of treatment outcomes in optic neuritis patients with and without demyelinating disease.
methodsA retrospective descriptive study of optic neuritis patients carried out between January 2009 and December 2016 was done. Univariate analysis and multivariate logistic regression analysis were used to evaluate the predictive factors of treatment outcomes.
resultsAmong 150 patients with optic neuritis, 58 patients were diagnosed with Neuromyelitis Optica Spectrum Disease (NMOSD), 23 patients were diagnosed with Multiple Sclerosis (MS) and 69 patients were idiopathic. The age at presentation in the NMOSD group was significantly younger than the MS group and the idiopathic group. The female:male ratio was significantly lower in the idiopathic group than in the NMOSD group. The initial Best Corrected Visual Activity (BCVA) of 20/20-20/60 (
conclusionNMOSD is a more common cause of optic neuritis than MS in Thai population. Female patients with poor initial VA, poor response to steroids treatment, and presenting recurrent attacks are highly suspicious for NMOSD. Optic neuritis without associated demyelinating disease has a better visual outcome and lower recurrence rate.
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