ArticleNeuro-ophthalmology (Aeolus Press)2018
Blepharospasm in Japan: A Clinical Observational Study From a Large Referral Hospital in Tokyo.
Article in Neuro-ophthalmology (Aeolus Press), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- The epidemiology and phenomenology of non-antipsychotic-induced dystonia: a hybrid systematic-narrative review.European psychiatry : the journal of the Association of European Psychiatrists · 2025Pooled it
- Efficacy and Safety of IncobotulinumtoxinA for the Treatment of Blepharospasm: A Multicenter, Phase 3 Study in Japan.Toxins · 2026Trial
- An Exploratory, Randomized, Double-Blind Clinical Trial of Dipraglurant for Blepharospasm.Movement disorders : official journal of the Movement Disorder Society · 2024Trial
- Comparative efficacy and safety of botulinum neurotoxin type A in blepharospasm and hemifacial spasm: a systematic review and Bayesian network meta-analysis.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- High-Density Glasses in Blepharospasm: Influence of Migraine and Early Morning Effects.Cureus · 2025Article
- Article
- Budget Impact Analysis of Botulinum Toxin Type A for Patients with Severe Blepharospasm in Thailand.ClinicoEconomics and outcomes research : CEOR · 2025Article
- Comparative analysis of onabotulinum toxin type-A injection techniques in older adults with blepharospasm: a retrospective cohort study.Frontiers in neurology · 2025Article
- Quantitative evaluation of blinking in blepharospasm using electrooculogram-integrated smart eyeglasses.Scientific reports · 2023Article
- The pathogenesis of blepharospasm.Frontiers in neurology · 2023Review
- Clinical Features and Evolution of Blepharospasm: A Multicenter International Cohort and Systematic Literature Review.Dystonia (Lausanne, Switzerland) · 2022Article
- Subjective assessment of effectiveness, quality of life, and psychological status of patients receiving botulinum toxin therapy for hemifacial spasm, blepharospasm, or cervical dystonia.Fujita medical journal · 2021Article
- Differences in detected safety signals between benzodiazepines and non-benzodiazepine hypnotics: pharmacovigilance study using a spontaneous reporting system.International journal of medical sciences · 2021Article
- Treatment of blepharospasm and Meige's syndrome with abo- and onabotulinumtoxinA: long-term safety and efficacy in daily clinical practice.Journal of neurology · 2020Observational
- Analysis of risk factors for Meige syndrome and construction and validation of a clinical prediction nomogram model.Frontiers in neurologyArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Focal dystonia is regarded as a characteristic feature of blepharospasm. However, patients do not always present with motor symptoms. To clarify the clinical features of blepharospasm in Japan, we conducted a retrospective observational study involving a large population of patients from a single institution. Common symptoms included difficulty opening the eyes, photophobia, and ocular pain/irritation. Initial symptoms often occurred following the long-term use of psychotropics such as etizoram, benzodiazepines, and zolpidem (32% of patients). Our findings demonstrated that the clinical presentation of blepharospasm is heterogenous, and that understanding regarding sensory-dominant forms of the disease may be poor among practitioners in Japan.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.