Evidence map›Paper›PMID 30258444›Full record

ArticleFrontiers in immunology2018

Shrimp Antiviral mja-miR-35 Targets

Yulei Chen, Siyuan Zhang, Jiao Cao, Xiaobo Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yulei ChenCollege of Life Sciences, Zhejiang University, Hangzhou, China.
Siyuan ZhangCollege of Life Sciences, Zhejiang University, Hangzhou, China.
Jiao CaoCollege of Life Sciences, Zhejiang University, Hangzhou, China.
Xiaobo ZhangCollege of Life Sciences, Zhejiang University, Hangzhou, China.
Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Virus infection can change host's metabolism, while tumorigenesis results from metabolic disorder. MicroRNAs (miRNAs), crucial regulatory factors overlaying transcriptional control mechanisms, can guide metabolic homeostasis. In terms of metabolic disorder, antiviral miRNAs may have anti-tumor activity. However, this issue has not been extensively investigated. In the present study, the results revealed that shrimp mja-miR-35, which showed antiviral activity in shrimp against white spot syndrome virus (WSSV) infection, could suppress the metastasis of breast cancer by targeting human

Indexed as

Breast NeoplasmsChitinase-3-Like Protein 1MacrophagesMicroRNAsPenaeidaeAnimalsFemaleHumansNeoplasm MetastasisTHP-1 CellsWhite spot syndrome virus 1CHI3L1 protein, humanChitinase-3-Like Protein 1MicroRNAsbreast cancer metastasishuman anti-tumorM2 macrophagemja-miR-35shrimp antivirus

Identifiers

PMID30258444
PMCPMC6143669
OpenAlexW2889843761

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.