Evidence map›Paper›PMID 30258433›Full record

ArticleFrontiers in immunology2018

Laura C Lighaam, Peter-Paul A Unger, David W Vredevoogd, Dorit Verhoeven, Ellen Vermeulen, Annelies W Turksma, Anja Ten Brinke, Theo Rispens, S Marieke van Ham

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
  2. Review
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  4. Article
  5. Review
  6. Regulatory B Cells in Tumor Microenvironment.Current issues in molecular biology · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. TLR9 Signaling Is Required for theInternational journal of molecular sciences · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Laura C LighaamDepartment of Immunopathology, Sanquin Research, Amsterdam, Netherlands.
Peter-Paul A UngerDepartment of Immunopathology, Sanquin Research, Amsterdam, Netherlands.
David W VredevoogdDepartment of Immunopathology, Sanquin Research, Amsterdam, Netherlands.
Dorit VerhoevenDepartment of Immunopathology, Sanquin Research, Amsterdam, Netherlands.
Ellen VermeulenDepartment of Immunopathology, Sanquin Research, Amsterdam, Netherlands.
Annelies W TurksmaDepartment of Immunopathology, Sanquin Research, Amsterdam, Netherlands.
Anja Ten BrinkeDepartment of Immunopathology, Sanquin Research, Amsterdam, Netherlands.
Theo RispensDepartment of Immunopathology, Sanquin Research, Amsterdam, Netherlands.
S Marieke van HamDepartment of Immunopathology, Sanquin Research, Amsterdam, Netherlands.
Amsterdam University Medical Centers · NLSanquin · NLUniversity of Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regulatory B cells (Breg) have been described as a specific immunological subsets in several mouse models. Identification of a human counterpart has remained troublesome, because unique plasma membrane markers or a defining transcription factor have not been identified. Consequently, human Bregs are still primarily defined by production of IL-10. In this study, we sought to elucidate if

Indexed as

Lymphocyte Activation3T3 CellsAnimalsB-Lymphocytes, RegulatoryFemaleFlow CytometryGene Expression RegulationHumansInterleukin-10Interleukin-6MaleMiceTumor Necrosis Factor-alphaIL10 protein, humanIL6 protein, humanInterleukin-10Interleukin-6Tumor Necrosis Factor-alphaB cell activationB cell plasticityBregcytokine co-expressionIL-10IL-6immune regulationt-SNE analysis

Identifiers

PMID30258433
PMCPMC6143818
OpenAlexW2889787113

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.