ReviewThe Yale journal of biology and medicine2018
Advances in Perfusion Systems for Solid Organ Preservation.
Review in The Yale journal of biology and medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Designer Organs: Ethical Genetic Modifications in the Era of Machine Perfusion.Annual review of biomedical engineering · 2025Review
- Real-time organ perfusion monitoring of human kidney transplants usingRoyal Society open science · 2025Article
- Methods of ex vivo analysis of tissue status in vascularized composite allografts.Journal of translational medicine · 2023Review
- Real-Time Monitoring Using Multiplexed Multi-Electrode Bioelectrical Impedance Spectroscopy for the Stratification of Vascularized Composite Allografts: A Perspective on Predictive Analytics.Bioengineering (Basel, Switzerland) · 2023Article
- Current practice and novel approaches in organ preservation.Frontiers in transplantation · 2023Review
- Evaluating the Performance of a Nonelectronic, Versatile Oxygenating Perfusion System across Viscosities Representative of Clinical Perfusion Solutions Used for Organ Preservation.Bioengineering (Basel, Switzerland) · 2022Article
- Electrocerebral Signature of Cardiac Death.Neurocritical care · 2021Article
- Zebrafish as a New Tool in Heart Preservation Research.Journal of cardiovascular development and disease · 2021Review
- Combination of mesenchymal stromal cells and machine perfusion is a novel strategy for organ preservation in solid organ transplantation.Cell and tissue research · 2021Review
- Macrophage depletion of CMV latently infected donor hearts ameliorates recipient accelerated chronic rejection.Transplant infectious disease : an official journal of the Transplantation Society · 2021Article
- Preservation solutions for attenuation of ischemia-reperfusion injury in vascularized composite allotransplantation.SAGE open medicine · 2021Article
- Oxygen Transport during Ex Situ Machine Perfusion of Donor Livers Using Red Blood Cells or Artificial Oxygen Carriers.International journal of molecular sciences · 2020Review
- Genome Sequences of Clinical Isolates of NDM-1-Producing Klebsiella quasipneumoniae subsp.Microbiology resource announcements · 2020Article
- Emerging organ-assist technology in cardiac procurement: a viewpoint.The Journal of international medical research · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the past, a diagnosis of organ failure would essentially be a death sentence for patients. With improved techniques for organ procurement and surgical procedures, transplantations to treat organ failure have become standard medical practice. However, while the demand for organs has skyrocketed, the donor pool has not kept pace leading to long recipient waiting lists. Organ preservation provides a means to increase the number of available transplantable organs. However, there are significant drawbacks associated with cold storage, the current gold standard. To address the short-comings due to diffusional limitations, engineers have developed cold perfusion systems. More recently, there has been a significant trend towards the development of near-normothermic systems to enhance the functional preservation of solid organs including livers, lungs, hearts, kidneys, and vascularized composite allotransplants. Here we review recent advances in the development of perfusion systems for the preservation of solid organs. We provide a brief history of organ transplantation, the limitations of existing systems, and describe research being done to develop commercially available perfusion systems to enhance organ preservation.
Indexed as
Identifiers
30258317PMC6153619What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.