ArticleOchsner journal2018
An Evidence-Based Opioid-Free Anesthetic Technique to Manage Perioperative and Periprocedural Pain.
Article in Ochsner journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Comparison of the effect of melatonin, dexmedetomidine, and gabapentin on reduction of postoperative pain and anxiety following laminectomy: a randomized clinical trial.BMC anesthesiology · 2022Trial
- Trial
- Safety and effectiveness of opioid-free anaesthesia in thoracoscopic surgery: a preliminary retrospective cohort study.BMC anesthesiology · 2024Observational
- Brief History of Opioids in Perioperative and Periprocedural Medicine to Inform the Future.Ochsner journal · 2023Review
- Opioid sparing effect of intravenous dexmedetomidine in orthopaedic surgery: a retrospective analysis.Journal of anesthesia, analgesia and critical care · 2022Article
- Opioid-free anesthesia in oncologic surgery: the rules of the game.Journal of anesthesia, analgesia and critical care · 2022Review
- Opioid-Free Epidural-Free Anesthesia for Open Hepatectomy: A Case Report.A&A practice · 2020Article
- Is an opioid-free anaesthesia possible without using alpha-2 agonists?Indian journal of anaesthesia · 2020Article
- Which idea is better with regard to immune response? Opioid anesthesia or opioid free anesthesia.Journal of inflammation research · 2020Review
- Article
- Opioid free onco-anesthesia: Is it time to convict opioids? A systematic review of literature.Journal of anaesthesiology, clinical pharmacologyReview
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe epidemic of opioid abuse is increasing, and the number of deaths secondary to opioid overdose is also increasing. Recent attention has focused on opioid prescribing and management of chronic pain. However, opioid use in perioperative and periprocedural patients, whether they have chronic pain or exhibit new persistent opioid abuse after a procedure, has received little attention.
methodsWe present an evidence-based technique that combines subanesthetic infusions of lidocaine and dexmedetomidine supplemented with other intravenous agents and a low dose of inhaled anesthetic.
resultsBased on evidence of drug action and interaction, an opioid-free anesthetic can be delivered successfully. We present the cases of 2 patients in whom the opioid-free anesthetic technique was used with a successful outcome, adequate pain management, and avoidance of opioid drugs.
conclusionThis anesthetic prescription can be useful for opioid-naïve patients as well as for patients with chronic pain that is managed with opioids.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.