Evidence map›Paper›PMID 30258282›Full record

ArticleMediators of inflammation2018

Circulating Th1, Th2, Th9, Th17, Th22, and Treg Levels in Aortic Dissection Patients.

Jing Ye, Yuan Wang, Zhen Wang, Qingwei Ji, Ying Huang, Tao Zeng, Haiying Hu, Di Ye, Jun Wan, Yingzhong Lin

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 75 citations in OpenAlex.

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  13. The mechanism and therapy of aortic aneurysms.Signal transduction and targeted therapy · 2023
    Review
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Jing YeDepartment of Cardiology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Yuan WangDepartment of Cardiology, Hubei Key Laboratory of Cardiology, Renmin Hospital of Wuhan University, Cardiovascular Research Institute, Wuhan University, Wuhan 430060, China.
Zhen WangDepartment of Cardiology, Hubei Key Laboratory of Cardiology, Renmin Hospital of Wuhan University, Cardiovascular Research Institute, Wuhan University, Wuhan 430060, China.
Qingwei JiDepartment of Cardiology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Ying HuangDepartment of Cardiology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Tao ZengDepartment of Cardiology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Haiying HuDepartment of Cardiology, Handan First Hospital, Handan 056002, China.
Di YeDepartment of Cardiology, Hubei Key Laboratory of Cardiology, Renmin Hospital of Wuhan University, Cardiovascular Research Institute, Wuhan University, Wuhan 430060, China.
Jun WanDepartment of Cardiology, Hubei Key Laboratory of Cardiology, Renmin Hospital of Wuhan University, Cardiovascular Research Institute, Wuhan University, Wuhan 430060, China.ORCID 0000-0003-4865-783X
Yingzhong LinDepartment of Cardiology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.ORCID 0000-0003-4424-0340
Wuhan University · CNCapital Medical University · CNThe People's Hospital of Guangxi Zhuang Autonomous Region · CNHandan College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious studies demonstrated that the subsets of CD4+ T helper (Th) cells are closely related to vascular diseases, including atherosclerosis and hypertension. This study is aimed at investigating the circulating Th1, Th2, Th9, Th17, Th22, and Treg levels in aortic dissection (AD) patients.

methodsBlood samples from AD (

resultsCompared with the levels in the NAD group, the Th1, Th9, Th17, Th22, and their transcription factor levels were increased and the Th2, Treg, and their transcription factor levels exhibited a decreasing trend in AD patients. In addition, higher IFN-

conclusionsChanges in Th1, Th2, Th9, Th17, Th22, and Treg activity are associated with the onset of AD. Different subsets of CD4+ T cells play different roles in the presence of AD.

Indexed as

Aortic DissectionApoptosisCD4-Positive T-LymphocytesCell LineEnzyme-Linked Immunosorbent AssayFemaleFlow CytometryHumansInterleukin-17Interleukin-22Interleukin-4Interleukin-9InterleukinsMaleMiddle AgedTh17 CellsInterleukin-17Interleukin-22Interleukin-4Interleukin-9Interleukins

Identifiers

PMID30258282
PMCPMC6146596
OpenAlexW2891674642

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.