Evidence map›Paper›PMID 30258265›Full record

ArticleAnnals of Indian Academy of Neurology

Predictors of Intracerebral Hemorrhage in Acute Stroke Patients Receiving Intravenous Recombinant Tissue Plasminogen Activator.

Vijay Chenna, Subhash Kaul, Swetha Tandra, Sireesha Yareeda, Neeharika Mathukumalli, Abhijeet Kumar Kohat, Rukmini Mridula Kandadai, Suryaprabha Turaga, Jabeen Afshan Sheik, A K Meena and 1 more

Abstract read
In one paragraph

Article in Annals of Indian Academy of Neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. The Association Between an Antecedent of Transient Ischemic Attack Prior to Onset of Stroke and Functional Ambulatory Outcome.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Vijay ChennaDepartment of Neurology, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.
Subhash KaulDepartment of Neurology, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.
Swetha TandraDepartment of Neurology, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.
Sireesha YareedaDepartment of Neurology, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.
Neeharika MathukumalliDepartment of Neurology, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.
Abhijeet Kumar KohatDepartment of Neurology, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.
Rukmini Mridula KandadaiDepartment of Neurology, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.
Suryaprabha TuragaDepartment of Neurology, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.
Jabeen Afshan SheikDepartment of Neurology, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.
A K MeenaDepartment of Neurology, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.
Rupam BorgohainDepartment of Neurology, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSymptomatic Intracerebral hemorrhage (sICH) is a serious complication of recombinant tissue-plasminogen activator (rt-PA) therapy for acute ischemic stroke (AIS).

objectiveTo estimate the prevalence and predictors of sICH in patients after receiving IV rt-PA for AIS. MATERIAL AND

methodsConsecutive patients of AIS thrombolysed between January 2010 and June 2016 in a University hospital in Hyderabad (India) were studied prospectively for sICH and it's various variables compared with the control group without sICH to determine any sigificantant difference.

resultsOut of 113 patients , sICH was detected in 12 (10.61%) whose mean age(58±12.0 years) and gender ratio ( 2:1 ) was not statistically significant from controls. In s ICH group mean NIHSS score was 16.53± 5.81 vs 10.19± 5.06 in controls (

conclusionHigh NIHSS score, increased stroke onset to thrombolysis time , high blood sugar at presentation ,prior diabetes and hypertension increase the chances of sICH. None of these contraindicate thrombolysing strokes but should caution the physician.

Indexed as

Indiaintracerebral hemorrhagestrokethrombolysis

Identifiers

PMID30258265
PMCPMC6137634

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.