ArticleNature2018
Mechanosensing by β1 integrin induces angiocrine signals for liver growth and survival.
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Article in Nature, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 103 papers.
0numbers the graph read from it
0cells of the map it votes in
103citing papers in PubMed
9.5field-weighted citation impact, top 1% of its field
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Who cites it
103 citing papers in PubMed, 166 citations in OpenAlex.
- Endothelial nitric oxide signaling in cellular and systemic metabolism.Redox biology · 2026Review
- Liver sinusoidal endothelial cell defenestration in chronic heart failure is primarily dependent on cardiac diastolic dysfunction and is reversed by a sodium-glucose cotransporter 2 inhibitor but not by an angiotensin-converting enzyme inhibitor.Cardiovascular research · 2026Article
- Liver regeneration governed by zonated PIEZO1 mechanotransduction.Cell regeneration (London, England) · 2026Article
- Haemodynamic control of zonated liver function via instructive vascular Wnt signalling.Nature communications · 2026Article
- Plasmin and sterile inflammation jointly drive fatal embryonic liver degeneration in endothelial chromatin remodeler mutant mice.Development (Cambridge, England) · 2026Article
- Mechanical Loading Induces Distinct and Shared Responses in Endothelial and Muscle Cells and Reveals Exercise-Like Molecular Profiles.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- Advances in In Vitro Vascularization of Engineered Tissues: From Microvessel Formation to Hepatic Tissue Integration.Regenerative therapy · 2026Article
- Nanoparticles reach metastatic tumours via enhanced permeability of adjacent vessels.Nature nanotechnology · 2026Article
- The Use of Single-Cell Mitochondrial DNA SNP Combinations for Distinguishing Organ-Specific Cell Types.Cells · 2026Article
- Magnetic torque-mediated early asymmetric mechanical stimulation directs structural and functional maturation in human cardiac organoids.Scientific reports · 2026Article
- Paracrine Factor Local Gradient-Generating System for Engineering Perfusable Vascularized Hepatocyte Tissues with Perfusion-Induced Proliferation.Advanced healthcare materials · 2026Article
- Transformative biomechanics and mechanobiology breakthroughs shaping the future of health and medicine.Innovation (Cambridge (Mass.)) · 2026Review
- Signal control during tissue regeneration in adult animals.Nature reviews. Molecular cell biology · 2026Review
- Three-dimensional bioprinted hiHeps hepatorganoids with enhanced hepatic functions for the treatment of liver failure and promotion of liver regeneration.Bioactive materials · 2026Article
- Evaluation of a 3,5-diethoxycarbonyl-1,4-dihydrocollidine diet-induced mouse model in a comparative experimental study of portal hypertension.World journal of gastroenterology · 2026Article
- Mechanical Environment Afforded by Engineered Hydrogel Critically Regulates Survival of Neural Stem Cells Transplanted in the Injured Spinal Cord via Piezo1-Mediated Mechanotransduction.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- A Multiphase CT-Based Radiomics-Clinical Model to Identify Inadequate Future Liver Remnant Hypertrophy After Portal Vein Embolization Before Major Hepatectomy.Cancer management and research · 2026Article
- Matrix stiffness maintains bladder cancer stemness via integrin-nuclear skeleton axis.Cell death & disease · 2025Article
- Article
- Galectin-3-integrin α5β1 phase separation disrupted by advanced glycation end-products impairs diabetic wound healing in rodents.Nature communications · 2025Article
43 more citing papers are in PubMed but not listed here.
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Authors and funding
19 authors at 5 institutions in 2 countries.
Linda Lorenz *Institute of Metabolic Physiology, Heinrich-Heine University, Düsseldorf, Germany.
Jennifer Axnick *Institute of Metabolic Physiology, Heinrich-Heine University, Düsseldorf, Germany.
Tobias BuschmannInstitute of Metabolic Physiology, Heinrich-Heine University, Düsseldorf, Germany.
Carina HenningInstitute of Metabolic Physiology, Heinrich-Heine University, Düsseldorf, Germany.
Sofia UrnerInstitute of Metabolic Physiology, Heinrich-Heine University, Düsseldorf, Germany.
Shentong FangThe Centre of Excellence in Translational Cancer Biology, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland.
Harri NurmiThe Centre of Excellence in Translational Cancer Biology, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland.
Nicole EichhorstClinic for Gastroenterology, Hepatology and Infectious Diseases, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
Richard HoltmeierDepartment of Cardiovascular Medicine, Division of Cardiology, University Clinic Münster, Münster, Germany.
Kálmán BódisGerman Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.
Jong-Hee HwangInstitute for Clinical Diabetology, German Diabetes Center (DDZ), Leibniz Center for Diabetes Research at Heinrich-Heine University, Düsseldorf, Germany.
Karsten MüssigGerman Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.
Daniel EberhardInstitute of Metabolic Physiology, Heinrich-Heine University, Düsseldorf, Germany.
Jörg StypmannDepartment of Cardiovascular Medicine, Division of Cardiology, University Clinic Münster, Münster, Germany.
Oliver KussGerman Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.
Michael RodenGerman Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.
Kari AlitaloThe Centre of Excellence in Translational Cancer Biology, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland.
Dieter HäussingerClinic for Gastroenterology, Hepatology and Infectious Diseases, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
Eckhard LammertInstitute of Metabolic Physiology, Heinrich-Heine University, Düsseldorf, Germany. lammert@hhu.de.
Heinrich Heine University Düsseldorf · DEDeutsches Diabetes-Zentrum e.V. · DEUniversity of Helsinki · FIGerman Center for Diabetes Research · DEUniversity of Münster · DE
Funding
No grant is acknowledged in the PubMed record.
Abstract
Angiocrine signals derived from endothelial cells are an important component of intercellular communication and have a key role in organ growth, regeneration and disease
Indexed as
Autocrine CommunicationSignal TransductionAnimalsCells, CulturedEndothelial CellsFemaleHepatocyte Growth FactorHepatocytesHumansIntegrin beta1LiverMaleMechanotransduction, CellularMiceMice, Inbred C57BLMiddle AgedFLT4 protein, humanHepatocyte Growth FactorIntegrin beta1Vascular Endothelial Growth Factor Receptor-3
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.