ArticleInternational journal of obesity (2005)2019
Severe obesity and cardio-metabolic comorbidities: a nationwide study of 2.8 million adolescents.
Article in International journal of obesity (2005), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 4 of them syntheses that pooled it.
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Who cites it
35 citing papers in PubMed, 4 syntheses or guidelines pooled it, 65 citations in OpenAlex.
- Adolescent obesity and risk of serious chronic morbidity and mortality in young adulthood: a systematic review of cohorts from national registries.Cardiovascular diabetology · 2026Pooled it
- The Global Spread of Severe Obesity in Toddlers, Children, and Adolescents: A Systematic Review and Meta-Analysis.Obesity facts · 2022Pooled it
- Adolescent and Childhood Obesity and Excess Morbidity and Mortality in Young Adulthood-a Systematic Review.Current obesity reports · 2021Pooled it
- Cardiovascular morbidity, diabetes and cancer risk among children and adolescents with severe obesity.Cardiovascular diabetology · 2020Pooled it
- Sociodemographic disparities in semaglutide and tirzepatide prescription for obesity treatment.Health affairs scholar · 2026Article
- Obesity in Late Adolescence and Healthcare Costs in Young to Mid-Adulthood.Diabetes, obesity & metabolism · 2026Article
- Assessment of BMI percentages of obesity thresholds and cardiometabolic risk factors in children and adolescents: a retrospective cross-sectional study in Beijing.Lipids in health and disease · 2026Article
- Adherence to Health Behavior Recommendations among Youth with Obesity Classes I, II, and III.Childhood obesity (Print) · 2026Article
- Trends in adolescent obesity in the Arab ethnic minority in Israel: an age-period-cohort analysis.BMC public health · 2025Article
- Adolescent Body Mass Index, Weight Trajectories to Adulthood, and Osteoporosis Risk.JAMA network open · 2025Article
- Physical fitness status and influencing factors among college students aged 19 ~ 22 in Shandong province, China: a cross-sectional study.BMC public health · 2025Article
- Detrimental Changes in Individual Health-Promoting Behaviors Among Internally Displaced Israelis.International journal of public health · 2025Article
- The Association of Weight Categories in Adolescence with Cardiovascular Morbidity in Young Adult Israeli Arabs-A Nationwide Study.Journal of clinical medicine · 2024Article
- The age of the obesity onset is a very important factor for the development of metabolic complications and cardiovascular risk in children and adolescents with severe obesity.European journal of pediatrics · 2024Article
- Article
- Examining Age-Adjusted Associations between BMI and Comorbidities in Mongolia: Cross-Sectional Prevalence.Healthcare (Basel, Switzerland) · 2024Article
- Article
- Cardiometabolic Improvements After Metabolic Surgery and Related Presurgery Factors.Journal of the Endocrine Society · 2024Article
- Physical activity, screen time and dietary behaviours in New Zealand adolescents prior to and following the onset of the COVID-19 pandemic.BMC public health · 2024Article
- Associations of adolescent obesity with hypertension, diabetes mellitus and polycystic ovaries in Arabs and Jews in Israel-a nationwide study.Frontiers in public health · 2024Article
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSevere obesity is rising among adolescents, but data on the prevalence of metabolic abnormalities among this group are limited. We assessed the secular trend of severe obesity and its association with major cardio-metabolic morbidities.
methodsA total of 2,785,227 Israeli adolescents (aged 17.2 ± 0.5 years) who underwent a pre-recruitment medical examination including routine measurements of weight, height and blood pressure between 1967 and 2015 were included. In all, 230,639 adolescents with abnormally excessive BMI were classified into overweight, classes I, II, and III (severe) obesity. Logistic regression was applied to determine the association between BMI groups and prehypertension, high blood pressure and type 2 diabetes (T2DM).
resultsThere was 45-fold increase in the prevalence of class III obesity during study period. Severe obesity was recorded in 2060 males and 1149 females, in whom nearly 35 and 43% had prehypertension or high blood pressure, respectively. Compared with adolescents with overweight, the odds ratios (ORs) for high blood pressure in classes II and III obesity groups, respectively, were 2.13 (95% CI, 2.04-2.23) and 2.86 (2.60-3.15) in males, and 2.59 (2.43-2.76) and 3.44 (3.04-3.90) in females, whereas the ORs for T2DM were 19.1 (12.3-29.6) and 38.0 (22.6-64.0) in males, and 15.1 (11.4-20.0) and 24.8 (17.2-35.7) in females. Results persisted in extensive sensitivity analyses including a longitudinal follow-up (median: males, 3.4 years; females, 4.9 years).
conclusionsSevere obesity showed a marked secular increase and was associated with significantly higher risk for abnormal blood pressure and T2DM than lower degrees of obesity, in both males and females.
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