Evidence map›Paper›PMID 30258012›Full record

ArticleJournal of virology2018

Visualization of Calcium Ion Loss from Rotavirus during Cell Entry.

Eric N Salgado, Brian Garcia Rodriguez, Nagarjun Narayanaswamy, Yamuna Krishnan, Stephen C Harrison

Open access · hybridAbstract read
In one paragraph

Article in Journal of virology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Article
  3. Mechanism of membrane perforation in rotavirus cell entry.bioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Fatty acid 2-hydroxylase facilitates rotavirus uncoating and endosomal escape.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Eric N SalgadoLaboratory of Molecular Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Brian Garcia RodriguezLaboratory of Molecular Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Nagarjun NarayanaswamyDepartment of Chemistry, University of Chicago, Chicago, Illinois, USA.
Yamuna KrishnanDepartment of Chemistry, University of Chicago, Chicago, Illinois, USA.
Stephen C HarrisonLaboratory of Molecular Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA harrison@crystal.harvard.edu.
Boston Children's Hospital · USUniversity of Chicago · US

Funding

STRUCTURE AND ASSEMBLY OF VIRUSES AND OF COATED VESICLESR01CA013202 · NCI · HARVARD UNIVERSITY · PI HARRISON, STEPHEN COPLAN · 1985 to 2024
$4.9M
Structure and Assembly of VirusesR37CA013202 · NCI · CHILDREN'S HOSPITAL BOSTON · PI HARRISON, STEPHEN COPLAN · 2003 to 2012
$3.7M
Howard Hughes Medical InstituteNCI NIH HHS R01 CA013202NCI NIH HHS R37 CA013202
6 · The paper itself

Abstract

Bound calcium ions stabilize many nonenveloped virions. Loss of Ca

Indexed as

AnimalsAntigens, ViralCalciumCapsidCapsid ProteinsCell LineCytosolFluorescent DyesMicroscopy, ConfocalProtein ConformationRotavirusVirus InternalizationAntigens, ViralCalciumCapsid ProteinsFluorescent DyesVP2 protein, RotavirusVP4 protein, RotavirusVP6 protein, RotavirusVP7 protein, RotavirusCa2+ sensorlive-cell imagingmembrane penetrationrotavirus entry

Identifiers

PMID30258012
PMCPMC6258952
OpenAlexW2893316155

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.