ArticleProceedings of the National Academy of Sciences of the United States of America2018
Functionally specific optogenetic modulation in primate visual cortex.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 52 citations in OpenAlex.
- Miniaturized optically generated Bessel beam ultrasound for volumetric transcranial brain stimulation.Science advances · 2026Article
- Iso-orientation bias of layer 2/3 connections unifies spontaneous, visually and optogenetically driven V1 dynamics.Nature communications · 2026Article
- Selective activation of mesoscale functional circuits via multichannel infrared stimulation of cortical columns in ultra-high-field 7T MRI.Cell reports methods · 2025Article
- Optogenetics and chemogenetics: key tools for modulating neural circuits in rodent models of depression.Frontiers in neural circuits · 2025Review
- Optogenetic Stimulation Recruits Cortical Neurons in a Morphology-Dependent Manner.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- A novel interface for cortical columnar neuromodulation with multipoint infrared neural stimulation.Nature communications · 2024Article
- Genetic Approaches for Neural Circuits Dissection in Non-human Primates.Neuroscience bulletin · 2023Review
- A unifying perspective on neural manifolds and circuits for cognition.Nature reviews. Neuroscience · 2023Review
- Towards translational optogenetics.Nature biomedical engineering · 2023Review
- Optogenetics in primate cortical networks.Frontiers in neuroanatomy · 2023Article
- Behavioral optogenetics in nonhuman primates; a psychological perspective.Current research in neurobiology · 2023Review
- Head-mounted optical imaging and optogenetic stimulation system for use in behaving primates.Cell reports methods · 2022Article
- Clinical Progress and Optimization of Information Processing in Artificial Visual Prostheses.Sensors (Basel, Switzerland) · 2022Review
- Review
- Vision Restoration by Optogenetic Therapy and Developments Toward Sonogenetic Therapy.Translational vision science & technology · 2022Article
- Chronically implantable LED arrays for behavioral optogenetics in primates.Nature methods · 2021Article
- Combining brain perturbation and neuroimaging in non-human primates.NeuroImage · 2021Review
- Infrared neural stimulation with 7T fMRI: A rapid in vivo method for mapping cortical connections of primate amygdala.NeuroImage · 2021Article
- Optical Imaging-Based Guidance of Viral Microinjections and Insertion of a Laminar Electrophysiology Probe Into a Predetermined Barrel in Mouse Area S1BF.Frontiers in neural circuits · 2021Article
- An Open Resource for Non-human Primate Optogenetics.Neuron · 2020Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
In primates, visual perception is mediated by brain circuits composed of submillimeter nodes linked together in specific networks that process different types of information, such as eye specificity and contour orientation. We hypothesized that optogenetic stimulation targeted to cortical nodes could selectively activate such cortical networks. We used viral transfection methods to confer light sensitivity to neurons in monkey primary visual cortex. Using intrinsic signal optical imaging and single-unit electrophysiology to assess effects of targeted optogenetic stimulation, we found that (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.