Evidence map›Paper›PMID 30257938›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Modulation of the Hippo pathway and organ growth by RNA processing proteins.

Jana Mach, Mardelle Atkins, Kathleen M Gajewski, Violaine Mottier-Pavie, Leticia Sansores-Garcia, Jun Xie, Robert Andrew Mills, Weronika Kowalczyk, Leen Van Huffel, Gordon B Mills and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Yorkie/YAP Interactors: Fine-Tuning the Hippo Pathway Output.Cold Spring Harbor perspectives in biology · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Emerging Roles of RNA-Binding Proteins in Neurodevelopment.Journal of developmental biology · 2022
    Review
  8. Review
  9. Exercise-induced changes in climbing performance.Royal Society open science · 2021
    Article
  10. Article
  11. Rox8 promotes microRNA-dependentProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Jana MachVlaams Instituut voor Biotechnologie (VIB) Center for Cancer Biology, University of Leuven, 3000 Leuven, Belgium.
Mardelle AtkinsVlaams Instituut voor Biotechnologie (VIB) Center for Cancer Biology, University of Leuven, 3000 Leuven, Belgium.
Kathleen M GajewskiDepartment of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Violaine Mottier-PavieVlaams Instituut voor Biotechnologie (VIB) Center for Cancer Biology, University of Leuven, 3000 Leuven, Belgium.
Leticia Sansores-GarciaVlaams Instituut voor Biotechnologie (VIB) Center for Cancer Biology, University of Leuven, 3000 Leuven, Belgium.
Jun XieVlaams Instituut voor Biotechnologie (VIB) Center for Cancer Biology, University of Leuven, 3000 Leuven, Belgium.
Robert Andrew MillsDepartment of Biological Sciences, Sam Houston State University, Huntsville, TX 77340.
Weronika KowalczykVlaams Instituut voor Biotechnologie (VIB) Center for Cancer Biology, University of Leuven, 3000 Leuven, Belgium.
Leen Van HuffelVlaams Instituut voor Biotechnologie (VIB) Center for Cancer Biology, University of Leuven, 3000 Leuven, Belgium.
Gordon B MillsDepartment of Biological Sciences, Sam Houston State University, Huntsville, TX 77340.
Georg HalderVlaams Instituut voor Biotechnologie (VIB) Center for Cancer Biology, University of Leuven, 3000 Leuven, Belgium; georg.halder@vib.be.
KU Leuven · BEVlaams Instituut voor Biotechnologie · BESam Houston State University · USThe University of Texas MD Anderson Cancer Center · US

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Drosophila Transgenic RNAi Resource ProjectR01GM084947 · NIGMS · HARVARD MEDICAL SCHOOL · PI PERRIMON, NORBERT · 2008 to 2019
$9.8M
Regulation of organ size in vivoR01GM067997 · NIGMS · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI HALDER, GEORG A · 2003 to 2011
$2.7M
NIGMS NIH HHS R01 GM067997NIGMS NIH HHS R01 GM084947NIH HHS P40 OD018537
6 · The paper itself

Abstract

The Hippo tumor-suppressor pathway regulates organ growth, cell proliferation, and stem cell biology. Defects in Hippo signaling and hyperactivation of its downstream effectors-Yorkie (Yki) in

Indexed as

Gene Expression Regulation, DevelopmentalAnimalsDrosophila melanogasterDrosophila ProteinsHeterogeneous-Nuclear Ribonucleoprotein Group F-HHeterogeneous-Nuclear RibonucleoproteinsNuclear ProteinsPoly(A)-Binding Protein IIRNA-Binding ProteinsSignal TransductionTrans-ActivatorsYAP-Signaling ProteinsDrosophila ProteinsGlo protein, DrosophilaHeterogeneous-Nuclear Ribonucleoprotein Group F-HHeterogeneous-Nuclear RibonucleoproteinsHrb27C protein, DrosophilaNuclear ProteinsPoly(A)-Binding Protein IIRNA-Binding Proteinssqd protein, DrosophilaTrans-ActivatorsYAP-Signaling ProteinsYki protein, DrosophilaaPKCHippo pathwayhnRNPHrb27CRNA-binding proteins

Identifiers

PMID30257938
PMCPMC6196505
OpenAlexW2893590138

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.