ArticleBMC genomics2018
Comparative genome analysis provides deep insights into Aeromonas hydrophila taxonomy and virulence-related factors.
Article in BMC genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Research on Prophages in Aquaculture from the Perspective of Paradigm Borrowing: Advances in Pathogen Virulence, Antimicrobial Resistance, and Environmental Regulation.Microorganisms · 2026Review
- The AsnC family regulator VU14_03665 modulates antibiotic resistance and acid tolerance in Aeromonas hydrophila AH10.Archives of microbiology · 2026Article
- Phylogenomic and comparative genomic analyses ofFrontiers in microbiology · 2026Article
- Genomic Insights into the Pathogenicity of HypervirulentPathogens (Basel, Switzerland) · 2025Article
- Advances and Challenges inVaccines · 2025Review
- Review
- Genotype diversity and antibiotic resistance risk in Aeromonas hydrophila in Sichuan, China.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024Article
- Genomic Characterization ofAntibiotics (Basel, Switzerland) · 2023Article
- Whole spectrum of Aeromonas hydrophila virulence determinants and the identification of novel SNPs using comparative pathogenomics.Scientific reports · 2023Article
- Aquatic Environments as Hotspots of Transferable Low-Level Quinolone Resistance and Their Potential Contribution to High-Level Quinolone Resistance.Antibiotics (Basel, Switzerland) · 2022Review
- Comparative Genomics of Typical and AtypicalMicroorganisms · 2022Article
- Article
- Reclassification of 11 Members of the Family Rhodobacteraceae at Genus and Species Levels and Proposal ofFrontiers in microbiology · 2022Article
- Characterization of a novel broad-spectrum endolysin PlyD4 encoded by a highly conserved prophage found in Aeromonas hydrophila ST251 strains.Applied microbiology and biotechnology · 2022Article
- Comparative Pathogenicity ofBiology · 2021Article
- VasH Contributes to Virulence ofFrontiers in veterinary science · 2021Article
- Genomic insight into the origins and evolution of symbiosis genes in Phaseolus vulgaris microsymbionts.BMC genomics · 2020Article
- An Update on the GenusMicroorganisms · 2020Review
- Identification of Antimicrobial Resistance Determinants inFrontiers in cellular and infection microbiology · 2020Article
- Comparative Study on A Novel Pathogen of European Seabass. Diversity ofMicroorganisms · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundAeromonas hydrophila is a potential zoonotic pathogen and primary fish pathogen. With overlapping characteristics, multiple isolates are often mislabelled and misclassified. Moreover, the potential pathogenic factors among the publicly available genomes in A. hydrophila strains of different origins have not yet been investigated.
resultsTo identify the valid strains of A. hydrophila and their pathogenic factors, we performed a pan-genomic study. It revealed that there were 13 mislabelled strains and 49 valid strains that were further verified by Average nucleotide identity (ANI), digital DNA-DNA hybridization (dDDH) and in silico multiple locus strain typing (MLST). Multiple numbers of phages were detected among the strains and among them Aeromonas phi 018 was frequently present. The diversity in type III secretion system (T3SS) and conservation of type II and type VI secretion systems (T2SS and T6SS, respectively) among all the strains are important to study for designing future strategies. The most prevalent antibiotic resistances were found to be beta-lactamase, polymyxin and colistin resistances. The comparative analyses of sequence type (ST) 251 and other ST groups revealed that there were higher numbers of virulence factors in ST-251 than in other STs group.
conclusionPublicly available genomes have 13 mislabelled organisms, and there are only 49 valid A. hydrophila strains. This valid pan-genome identifies multiple prophages that can be further utilized. Different A. hydrophila strains harbour multiple virulence factors and antibiotic resistance genes. Identification of such factors is important for designing future treatment regimes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.