Evidence map›Paper›PMID 30257480›Full record

ArticleInternational journal of molecular sciences2018

Porcine Breast Extracellular Matrix Hydrogel for Spatial Tissue Culture.

Girdhari Rijal, Jing Wang, Ilhan Yu, David R Gang, Roland K Chen, Weimin Li

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Advanced Hydrogels in Breast Cancer Therapy.Gels (Basel, Switzerland) · 2024
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Proteinaceous Hydrogels for Bioengineering Advanced 3D Tumor Models.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Review
  11. Article
  12. Article
  13. Extracellular Matrix in Development and Disease.International journal of molecular sciences · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Girdhari RijalDepartment of Biomedical Sciences, Elson S. Floyd College of Medicine, Washington State University, Spokane, WA 99202, USA. girdhari.rijal@wsu.edu.
Jing WangTissue Imaging and Proteomics Laboratory, Washington State University, Pullman, WA 99164, USA. jing.wang6@wsu.edu.
Ilhan YuSchool of Mechanical and Materials Engineering, Washington State University, Pullman, WA 99164, USA. ilhan.yu@wsu.edu.
David R GangTissue Imaging and Proteomics Laboratory, Washington State University, Pullman, WA 99164, USA. gangd@wsu.edu.
Roland K ChenSchool of Mechanical and Materials Engineering, Washington State University, Pullman, WA 99164, USA. roland.chen@wsu.edu.
Weimin LiDepartment of Biomedical Sciences, Elson S. Floyd College of Medicine, Washington State University, Spokane, WA 99202, USA. weimin.li@wsu.edu.
Washington State University · USWashington State University Spokane · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Porcine mammary fatty tissues represent an abundant source of natural biomaterial for generation of breast-specific extracellular matrix (ECM). Here we report the extraction of total ECM proteins from pig breast fatty tissues, the fabrication of hydrogel and porous scaffolds from the extracted ECM proteins, the structural properties of the scaffolds (tissue matrix scaffold, TMS), and the applications of the hydrogel in human mammary epithelial cell spatial cultures for cell surface receptor expression, metabolomics characterization, acini formation, proliferation, migration between different scaffolding compartments, and in vivo tumor formation. This model system provides an additional option for studying human breast diseases such as breast cancer.

Indexed as

Adipose TissueAnimalsBiocompatible MaterialsBreastCell Culture TechniquesCell LineCell Line, TumorCell MovementCell ProliferationCoculture TechniquesEpithelial CellsExtracellular Matrix ProteinsFemaleHumansHydrogelsMetabolomeBiocompatible MaterialsExtracellular Matrix ProteinsHydrogels3D culturebreast cancerextracellular matrixhydrogelporcinescaffoldtissue matrix scaffold

Identifiers

PMID30257480
PMCPMC6213433
OpenAlexW2893220017

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.