Evidence map›Paper›PMID 30257479›Full record

ArticleInternational journal of molecular sciences2018

The Risk G Allele of the Single-Nucleotide Polymorphism rs928413 Creates a CREB1-Binding Site That Activates

Alisa M Gorbacheva, Kirill V Korneev, Dmitry V Kuprash, Nikita A Mitkin

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

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  9. Glucocorticoid Receptor Binding Inhibits an IntronicInternational journal of molecular sciences · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alisa M GorbachevaLaboratory of Intracellular Signaling in Health and Disease, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow 119991, Russia. alisamur93@mail.ru.
Kirill V KorneevLaboratory of Intracellular Signaling in Health and Disease, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow 119991, Russia. kirkorneev@yandex.ru.
Dmitry V KuprashLaboratory of Intracellular Signaling in Health and Disease, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow 119991, Russia. kuprash@gmail.com.
Nikita A MitkinLaboratory of Intracellular Signaling in Health and Disease, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow 119991, Russia. mitkin.n.a@gmail.com.ORCID 0000-0002-1014-9250
Engelhardt Institute of Molecular Biology · RU

Funding

Russian Science Foundation 14-14-01140
6 · The paper itself

Abstract

Cytokine interleukin 33 (IL-33) is constitutively expressed by epithelial barrier cells, and promotes the development of humoral immune responses. Along with other proinflammatory mediators released by the epithelium of airways and lungs, it plays an important role in a number of respiratory pathologies. In particular, IL-33 significantly contributes to pathogenesis of allergy and asthma; genetic variations in the

Indexed as

Polymorphism, Single NucleotideAllelesAsthmaCell Line, TumorChildCyclic AMP Response Element-Binding ProteinEpithelial CellsGenetic Predisposition to DiseaseHumansInterleukin-33LungMAP Kinase Signaling SystemPromoter Regions, GeneticProtein BindingRespiratory MucosaTranscriptional ActivationCREB1 protein, humanCyclic AMP Response Element-Binding ProteinIL33 protein, humanInterleukin-33asthmainflammationlung epitheliump38 MAPK pathway

Identifiers

PMID30257479
PMCPMC6212888
OpenAlexW2893286836

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.