ArticleInternational journal of molecular sciences2018
Filamentous Aggregates of Tau Proteins Fulfil Standard Amyloid Criteria Provided by the Fuzzy Oil Drop (FOD) Model.
Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed.
- Hierarchical Structure of Protein Sequence.International journal of molecular sciences · 2021Article
- The Structure of Amyloid Versus the Structure of Globular Proteins.International journal of molecular sciences · 2020Article
- Structure of the Hydrophobic Core Determines the 3D Protein Structure-Verification by Single Mutation Proteins.Biomolecules · 2020Article
- Alternative Structures of α-Synuclein.Molecules (Basel, Switzerland) · 2020Article
- Model of Early Stage Intermediate in Respect to Its Final Structure.Biomolecules · 2019Article
- The Amyloid as a Ribbon-Like Micelle in Contrast to Spherical Micelles Represented by Globular Proteins.Molecules (Basel, Switzerland) · 2019Review
- Different Synergy in Amyloids and Biologically Active Forms of Proteins.International journal of molecular sciences · 2019Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Abnormal filamentous aggregates that are formed by tangled tau protein turn out to be classic amyloid fibrils, meeting all the criteria defined under the fuzzy oil drop model in the context of amyloid characterization. The model recognizes amyloids as linear structures where local hydrophobicity minima and maxima propagate in an alternating manner along the fibril's long axis. This distribution of hydrophobicity differs greatly from the classic monocentric hydrophobic core observed in globular proteins. Rather than becoming a globule, the amyloid instead forms a ribbonlike (or cylindrical) structure.
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Registered trials
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